In this procedure hemoglobin is converted to its reduced form and the magnitude of the zero-order spectral shift of the reduced hemoglobin peak at 430 nm to the carboxyhemoglobin peak at 418 nm is determined by second-derivative spectrum analysis. The method is simple, straightforward to set up, and rapid. A result may be obtained within 15 min of receiving the sample. It is sufficiently sensit...

Differential diagnosis of primary headache disorders can be challenging for physicians. Although the association of headache with acute carbon monoxide intoxication is very well-defined, in refractory nonspecific headaches associated with chronic low dose exposure to carbon monoxide, CO intoxication is usually overlooked, mostly due to vague symptoms. Herein we present a 15-year-old female pati...

Abstract Background Carbon monoxide causes electrical, functional, and morphological changes in the heart. It is unclear, however, whether indicators of myocardial damage can predict patient’s prognosis after carbon poisoning. This retrospective study aimed to investigate relationship between carboxyhemoglobin level electrocardiographic (ECG) ECG troponin I levels are related Methods Carboxyhem...

INTRODUCTION Surgery is supposed to modulate the production of carbon monoxide by the reduction of heme oxygenase activity or transcriptional regulation of inducible heme oxygenase. On the other hand, the inhalation of tobacco smoke can substantially raise the level of carboxyhemoglobin in the blood. Furthermore, methemoglobin is maintained at a constant level. However, excessive production of ...

Heme oxygenase 1 expression is increased in pediatric patients with malaria. The carboxyhemoglobin level (a measure of heme oxygenase 1 activity) has not been assessed in adult patients with malaria. Results of pulse co-oximetry revealed that the mean carboxyhemoglobin level was elevated in 29 Indonesian adults with severe falciparum malaria (10%; 95% confidence interval [CI], 8%-13%) and in 20...

partment patients. Respir Care 2013;57(2): 232-240. 2. Touger M, Birnbaum A, Wang J, Chou K, Pearson D, Bijur P. Performance of the RAD-57 pulse CO-oximeter compared with standard laboratory carboxyhemoglobin measurement. Ann Emerg Med 2010;56(4): 382-388. 3. Ruppel GL, Wilson HA, Gall VK, Hempkens JA. Multi-wavelength pulse oximeter is not suitable for adjusting DLCO measurements. Respir Care ...

We have developed a simple method for rapid determination of carboxyhemoglobin concentration in blood, by use of double-wavelength spectrophotometry. The absorbance of both oxyhemoglobin and reduced hemoglobin are instrumentally nulled out in this procedure, so that the absorption signal reflects HbCO and only a single spectrophotometric reading is required. This procedure is accurate in the ra...