نتایج جستجو برای: carboxymethylcellulose gel
تعداد نتایج: 106170 فیلتر نتایج به سال:
The aim of this study was to improve the transdermal permeation of Diclofenac Soduim. Permeation studies were carried out in -vitro using Cellophane Membrane. Topical gel formulations of diclofenac sodium were prepared by using Carbopol 934, Carbopol 940, sodium carboxymethylcellulose (NaCMC), polymer as a gel-forming material that is biocompatible and biodegradable. The skin permeation enhance...
Pressure ulcers are associated with significant rates of morbidity and mortality, particularly in the geriatric and spinal cord-injured populations. Newer pharmacologically active therapies include the use of topically applied recombinant human platelet-derived growth factor-BB (becaplermin), the active ingredient in REGRANEX) (becaplermin) Gel 0.01%, which has been approved in the United State...
Abstract The use of wood hemicelluloses, including galactoglucomannans (GGM) and glucuronoxylans (GX), in spray-dried microencapsulation bioactive compounds has not been reported. Our study aims to investigate the benefits GGM GX powders (sGGM sGX) along with effects homogenization techniques (magnetic stirring, ultrasonication, a combination UltraTurrax microfluidization) on physicochemical pr...
Environmental contamination with pesticides occurs at a global scale as result of prolonged usage and, therefore, their removal by low-cost and environmentally friendly systems is actively demanded. In this context, our study was directed to investigate the feasibility using some self-assembled hydrogels, comprising chitosan (CS) carboxymethylcellulose (CMC) or dialdehyde (DA)-CMC, for four com...
We have assessed whether viscoelastic gels known to inhibit mucociliary clearance can increase lipid-mediated gene transfer. Methylcellulose or carboxymethylcellulose (0.25-1.5%) was mixed with complexes of the cationic lipid GL67A and plasmids encoding luciferase and perfused onto the nasal epithelium of mice. Survival after perfusion with 1% CMC or 1% MC was 90 and 100%, respectively. In cont...
HYPOTHESIS The use of certain surgical adhesion reduction devices where there is a risk of concomitant bacterial contamination potentiates intra-abdominal infection. DESIGN Evaluation of adhesion reduction devices in an experimental model of intra-abdominal infection. SETTING Experimental animal model. INTERVENTIONS Adhesion reduction devices were administered at the time of bacterial cha...
Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications can have severe side effects. We have developed an injectable local antifungal treatment for direct administration into existing or potential sites of fungal infection. Amphotericin B (AmB), a hydrophobic...
PURPOSE The objective of this work was to develop a bioadhesive topical gel of sertaconazole nitrate with the help of response-surface approach. METHODS Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Carbapol 934 = X1) and Sodium carboxymethylcellulose (NaCMC) = X2)] on the bioadhesive character of gel, rheolo...
Complexes containing rat liver 80 S ribosomes, poly(uridylic acid), phenylalanyl-tRNA, elongation factor 1 alpha, and guanylyl(beta, gamma-methylene)-diphosphonate were prepared. Neighboring proteins in the complexes were cross-linked with the bifunctional reagent 2-iminothiolane. Proteins were extracted and then separated into 26 fractions by chromatography on carboxymethylcellulose. Each prot...
CONTEXT Endoscopic mucosal resection is an established modality for excision of sessile lesions in the gastrointestinal tract. Submucosal fluid injection creates a cushion and may prevent thermal injury and perforation. OBJECTIVES This blind study investigated the performance of three different solutions to create submucosal fluid cushions in porcine stomach. METHODS Three solutions were in...
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