PURPOSE To prospectively evaluate whether cardiac gating can improve the reproducibility of intravoxel incoherent motion (IVIM) parameters in the head and neck, we performed IVIM diffusion-weighted imaging (DWI) using 4 b values (4b), 4 b values with cardiac gating (4b gating) and 17 b values (17b). METHODS We performed IVIM DWI twice per person on nine healthy volunteers using 4b, 4b gating ...

Cardiac phase determination of 3D ultrasound (US) imaging has numerous applications including intraand inter-modality registration of US volumes, and gating of live images. We have developed a novel and potentially clinically useful real-time three-dimensional (3D) cardiac motion gating technique that facilitates and supports 3D USguided procedures. 0ur proposed real-time 3D-Masked-PCA techniqu...

INTRODUCTION Free-breathing cardiac cine imaging with respiratory and cardiac self-gating provides flexibility and convenience for patient scans. Here we propose a 3D radial cardiac cine imaging technique that improves upon self-gating by adding 3D respiratory motion correction. The 3D respiratory motion signals are derived from multiple projections through the data used for image reconstructio...

With the advent of multislice CT more than a decade ago, multislice CT angiography has demonstrated a huge potential in the less invasive imaging of cardiovascular disease, especially in the diagnosis of coronary artery disease. The diagnostic accuracy of multislice CT angiography has been significantly augmented with the rapid technical developments ranging from the initial 4-slice, to the cur...

The gating charge and voltage dependence of the open state to the inactivated state (O-->I) transition was measured for the voltage-dependent mammalian cardiac Na channel. Using the site 3 toxin, Anthopleurin-A (Ap-A), which selectively modifies the O-->I transition (see Hanck, D. A., and M. F. Sheets. 1995. Journal of General Physiology. 106:601-616), we studied Na channel gating currents (Ig)...

Voltage-gated sodium channel function from neonatal and adult rat cardiomyocytes was measured and compared. Channels from neonatal ventricles required an approximately 10 mV greater depolarization for voltage-dependent gating events than did channels from neonatal atria and adult atria and ventricles. We questioned whether such gating shifts were due to developmental and/or chamber-dependent ch...

Background Coronary arteries remain challenging structures to image using MRI due to the small size, tortuous course, and continual motion. Current high-resolution whole-heart techniques use prospective ECG-triggering and navigator gating to suppress cardiac and respiratory motion artifacts, respectively. However, these motion suppression strategies only accept data acquired within a narrow win...