UNLABELLED The purpose of this clinical trial was to evaluate the effect of the Terumo Capiox FX05 oxygenator with integrated arterial filter during cardiopulmonary bypass (CPB) compared with the Terumo Capiox RX05 Baby RX and arterial filter on inflammatory mediators and blood product utilization. Forty patients weighing less than 10 kg who underwent congenital heart surgery utilizing cardiopu...

OBJECTIVE This study aimed to compare the effects of two different perfusion techniques: conventional cardiopulmonary bypass and miniature cardiopulmonary bypass in patients undergoing cardiac surgery at the University Hospital of Santa Maria--RS. METHODS We perform a retrospective, cross-sectional study, based on data collected from the patients operated between 2010 and 2013. We analyzed th...

conclusions there was no difference in clinical outcome after cardiac surgery when we administered an additional dose of methylprednisolone compared to a single dose of methylprednisolone. patients and methods sixty pediatric patients (age < 5years) undergoing cardiopulmonary bypass surgery between september 2011-2012 at imam reza hospital-mashhad were randomly assigned to receive preoperative ...

Conventional cardiopulmonary bypass can trigger a systemic inflammatory response syndrome similar to sepsis. Aetiological factors include surgical trauma, reperfusion injury, and, most importantly, contact of the blood with the synthetic surfaces of the heart-lung machine. Recently, a new cardiopulmonary bypass system, mini-extracorporeal circulation (MECC), has been developed and has shown pro...

Pulmonary injury during cardiopulmonary bypass is common as patient factors (smoking, pain, pneumonia) and the effects of cardiopulmonary bypass combine to compromise lung function after cardiac surgery. Lung injury follows the propagation of an inflammatory response involving cytokines, complement, neutrophils, monocytes, activated endothelial cells and platelets. Neutrophils sequester in the ...

We read with a great interest the excellent article by Onorati and co-workers demonstrating that pulsatile cardiopulmonary bypass (PCPB) and off-pump coronary artery bypass (OPCAB) surgery markedly reduced endothelial activation and inflammatory response as compared with linear CPB [1]. What about anti-inflammatory cytokines (except interleukin (IL)-10 already investigated in this study)? Studi...

Sixteen patients undergoing coronary revascularization requiring cardiopulmonary bypass received remifentanil 2 micrograms kg-1 or 5 micrograms kg-1 by infusion over 1 min after sternotomy but before commencing cardiopulmonary bypass, during hypothermic cardiopulmonary bypass and during cardiopulmonary bypass after rewarming. Hypothermic cardiopulmonary bypass reduced the clearance of remifenta...