OBJECTIVE The aim of this study was to present the surgical findings of children with Waardenburg syndrome (WS) and investigate speech development after cochlear implantation in this unique group of patients. MATERIALS AND METHODS A retrospective chart review of the patients diagnosed with WS and implanted between 1998 and 2015 was performed. Categories of auditory performance (CAP) test were...

OBJECTIVE The aim of this study was to investigate auditory cortical development using mismatch negativity (MMN) in prelingual severe-to-profound hearing-impaired children from the stage of cochlear implant (CI) power-up to 6 months after power-up. METHOD Eighteen children were recruited and examined at the stage of CI initial power-up (M0), as well as several follow-up periods, that is, 1 mo...

OBJECTIVES/HYPOTHESIS To explore the genetic characteristics of children with cochlear implants (CIs) and to correlate the auditory performance after implantation to the genetic diagnosis of children with CIs. STUDY DESIGN Prospective cohort study. METHODS Mutations of four common deafness-associated genes, GJB2, SLC26A4, the mitochondrial 12S rRNA gene, and OTOF, were screened in 743 unrel...

Background: The aim of this study was to determine the auditory performance of congenitally deaf children and the effect of cochlear implantation (CI) on speech intelligibility. Methods: A prospective study was undertaken on 47 children in a pediatric tertiary referral center for CI. All children were deaf prelingually and were younger than 8 years of age. They were followed up until 5 years af...

OBJECTIVE To assess whether speech therapy can lead to better results for early cochlear implantation (CI) children. PATIENTS A cohort of thirty-four congenitally profoundly deaf children who underwent CI before the age of 18 months at the Sixth Hospital affiliated with Shanghai Jiaotong University from January 2005 to July 2008 were included. Nineteen children received speech therapy in reha...

OBJECTIVES To evaluate retrospectively, the possible difference in diffusion tensor imaging (DTI) metric of fractional anisotropy (FA) between good and poor surgical outcome cochlear implantation (CI) patients using investigator-independent voxel-wise analysis. METHODS Eighteen patients (11 males, 7 females; mean age, 5.9 years) with profound sensorineural hearing loss underwent DTI scans usi...

Spoken language acquisition is challenging for very young deaf or hard-of-hearing children (DHH) who wear hearing aids cochlear implants (CI). Timely decision-making treatment essential these and requires suitable assessments. Two such assessments are the Categories of Auditory Performance Index II (CAP-II) Speech Intelligibility Rating Scale (SIR). These have been shown to be helpful ongoing e...

OBJECTIVES This study aims to investigate the effects of age factor on the long-term efficacy of cochlear implantation. PATIENTS AND METHODS The electronic records of patients, who underwent cochlear implantation with the initial diagnosis of bilateral severe to profound sensorineural hearing loss in our clinic between January 2001 and December 2008, were analyzed retrospectively. The patient...

PURPOSE Our objective was to evaluate age-dependent changes in microstructure and metabolism in the auditory neural pathway, of children with profound sensorineural hearing loss (SNHL), and to differentiate between good and poor surgical outcome cochlear implantation (CI) patients by using diffusion tensor imaging (DTI) and magnetic resonance spectroscopy (MRS). MATERIALS AND METHODS Ninety-t...