in the present work a ph-dependent cloud point extraction procedure using ph-sensitive hydrogel polymer was applied for preconcentration and spectrophotometric determination of the hg(ii) as its thio micher's ketone complex. central composite design (ccd) and response surface method were applied to design the experiments and find out the optimum conditions. four factors entitled concentration o...

this paper describes optimization method that combines the plackett-burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of l-asparaginase by serratia marcescens sb08. four medium factors, from out of 11 medium factors, were screened by plackett-burman design experiments and subsequent optimization process to find out the o...

This paper is concerned with the statistical model development issues, necessary for rapid estimation of the rotor sizing for single main rotor helicopters at the preliminary design stage. However, Central Composite Design (CCD) method, simulation-based data collection, linear regression analysis, mathematical modelsdevelopmentand validations through the analysis of variance (ANOVA) were perfor...

background and objective: in the present study, bacillus polymyxa ncim no. 2539 was selected to utilize agro-industrial byproduct (orange peel) for amylase production under submerged fermentation conditions. material and methods: different agro-industrial byproducts like cane molasses, wheat bran, rice bran and orange peel were screened for maximum amylase production. amylase activitiy of bacil...

in the present study lactic acid production was enhanced by optimizing the three process variables viz; inoculum size, temperature and ph using three factor five level ccrd (central composite rotatable design) by lactobacillus delbruckii under smf (submerged fermentation process). paneer (dairy by-product) whey was used as sole substrate for lactic acid production. design expert 8.0.2.0 softwar...

The aim of this investigation was to prepare, characterize and optimize the aceclofenac proniosomes using central composite design and carry out stability studies. Three independent variables selected were molar ratio of drug to lipid (X1), surfactant loading (X2) and volume of hydration (X3). Based on central composite design, 16 batches of proniosomes were prepared by slurry method and evalua...

The aim of this investigation was to prepare, characterize and optimize the aceclofenac proniosomes using central composite design and carry out stability studies. Three independent variables selected were molar ratio of drug to lipid (X1), surfactant loading (X2) and volume of hydration (X3). Based on central composite design, 16 batches of proniosomes were prepared by slurry method and evalua...

Biological treatment, especially enzymatic methods, can be employed for effective and environmental- friendly treatment of dye effluents. Laccase, belonging to the blue multi-copper oxidases category, can oxidize a wide variety of substrates, especially synthetic dyes. In this study, laccase was used to biodegrade two azo dyes, i.e., Direct Red 23 and Acid Blue 92. Before conducting the exp...