PURPOSE To describe retinotopic mapping of the visual cortex when a central scotoma is present. DESIGN Single observational case report. METHODS Scanning laser ophthalmoscope perimetry was used to define the site and stability of fixation and the area of dense scotoma. Functional magnetic resonance imaging of the visual cortex was performed while the patient viewed an expanding annular stim...

In the contextual cueing paradigm, incidental visual learning of repeated distractor configurations leads to faster search times in repeated compared to new displays. This contextual cueing is closely linked to the visual exploration of the search arrays as indicated by fewer fixations and more efficient scan paths in repeated search arrays. Here, we examined contextual cueing under impaired vi...

Unilateral acute idiopathic maculopathy (UAIM) is an uncommon inflammatory disease of the retinal pigment epithelium (RPE) that affects young adults. The variability of clinical features of UAIM makes the diagnosis cumbersome. We report on a 25-year-old man with sudden loss of visual acuity (VA) and a central scotoma in his right eye. Fluorescein angiography localised the lesion in the RPE. Mic...

PURPOSE To investigate the risk factors for initial central scotoma (ICS) compared with initial peripheral scotoma (IPS) in normal-tension glaucoma (NTG). METHODS Fifty-six NTG patients (56 eyes) with an ICS and 103 NTG patients (103 eyes) with an IPS were included. Retrospectively, the differences were assessed between the two groups for baseline characteristics, ocular factors, systemic fac...

Some eye diseases, especially macular degeneration, can cause central vision loss (CVL), impairing goal-driven guidance of attention. Does CVL also affect implicit, experience-driven attention? We investigated how simulated scotomas affected young adults' ability to prioritize locations frequently containing visual search targets (location probability learning). Participants searched among dist...

Background: Reading withh a central scotoma involves the use of preferredd retinal loci (PRLs) that enables bothh letter resolutionn and global viewing of word.. Spontaneously-developedd PRLs however oftenn privilege spatial resolutionn and,, as a result,, visual spann is commonly limitedd by the positionn of the scotoma.. Inn this study we evaluatedd a trainingg procedure aimedd at improving o...

Age-related macular degeneration (AMD), affecting the retina, afflicts one out of ten people aged 80 years or older in the United States. AMD often results in vision loss to the central 15-20 deg of the visual field (i.e. central scotoma), and frequently afflicts both eyes. In most cases, when the central scotoma includes the fovea, patients will adopt an eccentric preferred retinal locus (PRL)...