I . Hayes, J. I). & Wolf. C. R. ( IYSX) in Ghituthione (’onjugation (Sies, H. & Ketterer. 8.. eds), pp. 315-355. Academic Press Limited, London 2. Meister. A. ( 1980) in Ghrtrithione: Chemicul, Biochemical, mid Medical Aspc~rts (Dolphin, D.. Poulson. R. & Avramovic, 0.. A), pp. 307-474, John Wiley & Sons. New York 3. Kramer, R. A,, Zakher, J. & Kim, G. (1988) Science 241, 604-696 -1. Riirlamh. ...

Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays...

From the *Department of Medicine, Tufts University School of medicine and New England Medical Center, Boston, Massachusetts 02111; the *Department of Biology, Tufts University, Medford, Massachusetts 02152; the OLaboratory of Medical Biochemistry, Rockefeller University, New York 10021; and the Departments of U Pharmacological Science and ~Medicinal Analytical Chemistry, Genentech, Inc., South ...

Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays...

Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays...

Abstract We prove the existence of a ground state positive solution Schrödinger–Poisson systems in plane form \[ -\Delta u + V(x)u \frac{\gamma}{2\pi} \left(\log|\cdot| \ast u^2 \right)u = b |u|^{p-2}u \quad\text{in}\ \mathbb{R}^2, \] where $p\ge 4$ , $\gamma,b>0$ and potential $V$ is assumed to be unbounded at infinity. On we do not require any symmetry or periodicity assumption, it suppose...

In the early 1980s, in search of the cytokine that triggers disease- associated weight loss and lethal shock, Anthony Cerami and Bruce Beutler purified "cachectin." They soon found out that their malevolent cytokine already had another name-tumor necrosis factor (TNF)-and was being lauded as a potential antitumor agent.

and Applied Analysis 3 2. Mathematical Background and Hypotheses Let X be a Banach space, and let X∗ be its topological dual. By 〈·, ·〉 we denote the duality brackets for the pair X∗, X . Let φ ∈ C1 X . We say that φ satisfies the Cerami condition if the following is true: “every sequence {xn}n≥1 ⊆ X, such that {φ xn }n≥1 is bounded and 1 ‖xn‖ φ′ xn −→ 0 in X∗, 2.1 admits a strongly convergent ...

In this paper, we prove the existence of nontrivial nonnegative solutions to a class of elliptic equations and systems which do not satisfy the Ambrosetti– Rabinowitz (AR) condition where the nonlinear terms are superlinear at 0 and of subcritical or critical exponential growth at ∞. The known results without the AR condition in the literature only involve nonlinear terms of polynomial growth. ...