background: hyperthyroidism as a risk factor for stroke is not conclusive. there are no definite data on the relationship between ischemic cerebrovascular injury and hyperthyroidism. this study was designed to define whether the outcomes of post-ischemic stroke injury are influenced by chronic hyperthyroidism. methods: two groups of hyperthyroid (ht) and control euthyroid rats of equal numbers ...

numerous etiologies are responsible for cases of stroke in young adults. this study reviews the causes of two types of stroke (ischemic and intracerebral hemorrhage) in young adults aged 15 to 40years, admitted to our center (a tertiary care center) from 1997 to 2002. the purpose of this study is to determine the relative frequency of causes of stroke in young adults and compare this with publi...

BACKGROUND AND PURPOSE The results of the Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS), a randomized double-blind study of sarpogrelate (selective 5-HT(2A) receptor antagonist) versus aspirin in 1510 Japanese patients, have been reported. But S-ACCESS failed to demonstrate noninferiority of sarpogrelate to aspi...

Cerebrovascular events increase with additional risk factors in patients with nonvalvular atrial fibrillation (NVAF). The relative risk proportional to the number of risk factors in Japanese patients has not been reported. The prevalence of risk factors was investigated for over 2 years in a prospective cohort study of 265 patients with NVAF. The CHADS2 score is a widely used risk stratificatio...

BACKGROUND Fibrinogen-depleting agents are promising in the treatment of cerebral ischemic disease. They were studied by many trials, and the outcomes were different because of different regimens and different doses. In this study, we assessed the efficacy and safety of defibrase on acute cerebral infarction in China. METHODS A search using Chinese hospital knowledge database (CHKD) and MEDLI...

Objective(s): Carthamus tinctorius L. (CT) or saffloweris widely used in traditional Chinese medicine. This study investigated the effects of CT extract (CTE) on ischemia–reperfusion (I/R) brain injury and elucidated the underlying mechanism. Materials and Methods: The I/R model was conducted by occlusion of both common carotid arteries and right middle cerebral artery for 90 min followed by 24...

The impact of blood pressure, serum cholesterol and triglycerides, and smoking on the risk of cerebral infarction and other stroke was studied by a longitudinal design. A random sample of the population aged 35-59 years in two counties of Eastern Finland was examined in 1972, with a participation rate of 92 per cent. In subjects (both sexes) standardized epidemiological measurements on blood pr...

The impact of blood pressure, serum cholesterol and triglycerides, and smoking on the risk of cerebral infarction and other stroke was studied by a longitudinal design. A random sample of the population aged 35-59 years in two counties of Eastern Finland was examined in 1972, with a participation rate of 92 per cent. In subjects (both sexes) standardized epidemiological measurements on blood pr...

objective(s): carthamus tinctorius l. (ct) or saffloweris widely used in traditional chinese medicine. this study investigated the effects of ct extract (cte) on ischemia–reperfusion (i/r) brain injury and elucidated the underlying mechanism. materials and methods: the i/r model was conducted by occlusion of both common carotid arteries and right middle cerebral artery for 90 min followed by 24...