cerebral venous thrombosis, including thrombosis of cerebral veins and major dural sinuses, is an uncommon disorder in the general population. however, it has a higher frequency among patients younger than 40 years of age, patients with thrombophilia, pregnant patients or those receiving hormonal contraceptive therapy or has foreign body such as catheter in their veins or arterial system. in th...

background: evidence is accumulating that venous thromboembolism is not limited to coagulation system and immune system seems to be involved in formation and resolution of thrombus. some studies have demonstrated the role of inflammatory factors in deep venous thrombosis (dvt) of limbs; however, there has not been such study in the patients with cerebral venous sinus thrombosis (cvst). the purp...

introduction : activated protein c (apc) inactivates factor v by cleavage of its heavy chain at arg306, arg506, arg679, and lys994. mutational changes, which abolish apc cleavage sites, may predispose thrombosis by altering the inactivation process of factor v.  factor v leiden (arg506glu) has been demonstrated as a strong risk factor for thrombosis. in the current study, we have studied whethe...

infection-related cerebral venous sinus thrombosis (cvst) is a rare cerebral vascular diseases which has no pathognomonic sign or definite diagnostic approach. it is crucial to early suspect and recognize the disease to lower morbidity and mortality of it. however, its low incidence and atypic presentation often leads to misdiagnosis and treatment delay which increase complications and mortalit...

background: septic intracranial venous thrombosis is a rare vascular disease of the brain with no specific sign or symptom. while urgent treatment will result in complete recovery, delays may cause permanent complications or even death. case report: the patient was a 23-year-old woman who had suffered visual loss, hallucination, and confusion two weeks after undergoing submandibular abscess rem...

This is a case study of a 34-year-old woman who was admitted to hospital with a history of severe orthostatic headache. She was diagnosed as having spontaneous intracranial hypotension (SIH) by undetectable cerebrospinal fluid (CSF) pressure at lumbar puncture, and with evidence of diffuse dural enhancement of the brain detected by magnetic resonance imaging (MRI). However, the contrast-enhance...

Cerebral venous sinus thrombosis (CVST) is a severe and rare pregnancy complication. The most common symptom headache. However, it less for headaches to be accompanied by seizures. Postpartum eclampsia (PPE) traditionally refers convulsions within seven days, but can occur up 4 weeks after birth. In this case report, we present our patient who developed cerebral thrombosis, which very complicat...

Introduction: Extreme altitude travel has gained popularity globally for adventurous, scientific, and military endeavors. Cerebral venous sinus thrombosis (CVST) at extreme altitude is a rare, covert, and emergent condition requiring immediate intervention. Case Presentation: A case of CVST masqueraded as high altitude cerebral edema (HACE) at 6700 m/22000 ft i...

Objective: The clinical value of IgG anticardiolipin antibody in patients with Behçet's disease with or without vascular thrombosis was evaluated.   Methods: IgG isotype of anticardiolipin (aCL) antibody was assessed in 40 Behçet's disease (BD) patients with venous or arterial thrombosis, 40 BD patients without venous or arterial thrombosis and 80 healthy subjects as controls. The levels of IgG...

although cerebral venous thrombosis is an uncommon cause of stroke among the young, it is being increasingly recognised. a prothrombotic risk factor is identified in the majority of the patients. in most instances it is seen in women in the post-partum period and those on oral contraceptives. magnetic resonance imaging (mri) has improved our ability to diagnose this condition however the variab...