In the course of studies conducted in this laboratory on the distribution and concentration of metal ions in the central nervous system (CNS),'3 similar studies were made on the cerebrospinal fluid (CSF). Of the fifteen ions found in the CNS tissue, only four (Na, K, Mg, and Ca) were found consistently, and Cu occasionally in CSF. The role of magnesium in biological systems has been well studie...

The cause of preeclampsia remains unknown and calcium and magnesium supplement are being suggested as means of prevention. The objective of this study was to assess magnesium and calcium in the plasma and cerebrospinal fluid of Nigerian women with preeclampsia and eclampsia. Setting was University of Benin Teaching Hospital, in Nigeria. It was a cross-sectional study comprising of eleven patien...

The very narrow limits within which the levels of cerebrospinal fluid (CSF) calcium, magnesium, and their ratio, are maintained have been reported from this laboratory.8 The data obtained from patients without signs of neurological condition or psychosis are in good agreement with the results obtained by Stutzman and Amatusio.1' CSF calcium is at 4.95 mg.%4± 0.11, magnesium at 3.01 mg.% ±0.03, ...

many diseases are related to cerebrospinal .uid (csf) hydrodynamics. therefore, understanding the hydrodynamics of csf .ow and intracranial pressure is helpful for obtaining deeper knowledge of pathological processes and providing better treatments. furthermore, engineering a reliable computational method is promising approach for fabricating in vitro models which is essential for inventing gen...

Cerebrospinal fluid (CSF) is an ultrafiltrate of plasma formed by active, ATP-dependent pumps located predominantly in the choroidal epithelium. CSF is continuously produced and absorbed, turning over approximately 3-4 times per day. CSF normally is colorless, odorless, and contains very few cells. Compared to serum, CSF is low in protein, glucose, potassium and calcium, but high in sodium, mag...

background and objective: febrile convulsions (fc) are the most common seizure disorders in children. lumbar puncture should be considered in any case with fc who is suspected to intracranial infections. this study determined white blood cell and polymorphonuclear cell counts, protein and glucose levels in cerebrospinal fluids (cfs) of children that were hospitalized with fc. methods: in this c...

background and objectives: encephalitis can cause a severe public health problem. the main aim of this research was to evaluate the medical laboratory results of patients with herpes simplex virus (hsv) encephalitis. materials and methods: diagnosis of encephalitis for these patients was firstly based on a clinical profile for herpes simplex encephalitis (hse), plus either a detected hsv1&2-dna...

Despite much research, there remains controversy over the role of gap junctions in seizure processes. Many studies report anticonvulsant effects of gap junction blockade, but contradictory results have also been reported. The aim of this study was to clarify the role of connexin36 (Cx36) gap junctions in neocortical seizures. We used the mouse neocortical slice preparation to investigate the ef...

An extension of the previously proposed model of Mg metabolism (Robson et al. 1997) has been developed to consider the transactions of Mg that are associated with cerebrospinal fluid (CSF) and bone. The representation of the CSF as a single MG compartment with uptake from the plasma described by Michaelis-Menten kinetics gives very good agreement with published experiments. Analysis of the avai...