The goal of this study was to detect the long-term effect of shunting on the integrity of white matter in young children with hydrocephalus.The authors reported the case of a 6-month-old boy with hydrocephalus who was evaluated by diffusion tensor imaging (DTI) before and after a shunt operation.When compared with normal children, the structures of the corpus callosum, internal capsule, and cor...

The aim of this study was to determine whether the improvement of cerebrospinal fluid (CSF) flow dynamics by CSF shunting, can suppress the oligomerization of amyloid β-peptide (Aβ), by measuring the levels of Alzheimer's disease (AD)-related proteins in the CSF before and after lumboperitoneal shunting. Lumbar CSF from 32 patients with idiopathic normal pressure hydrocephalus (iNPH) (samples w...

The case of a child admitted to hospital with acute onset of hemiparesis and seizure is presented. Extensive evaluation of an acute ischemic event in the form of a brain infarct found on brain magnetic resonance imaging was inconclusive. Two months later, the patient was referred with severe hydrocephalus, which was managed with ventriculoperitoneal shunting in the presence of normal ventricula...

Liquorpheresis (cerebrospinal fluid filtration) comprises a therapeutical approach that has been proposed to treat several neurological conditions where antibodies, inflammatory mediators, or abnormal peptides are the cause or play an important role in the pathogenesis of the disease. Continuous or intermittent cerebrospinal fluid (CSF) replacement may be an alternative approach not explored th...

enterobius vermicularis is a nematod of large intestine in man. extra intestinal localization of this parasite is rare. a 60 year old man was admitted to the hospital with the clinical manifestation of meningitis. in laboratory examination of cerebrospinal fluid (c.s.f), the appearance was red, albu-min level was high and the glucose showed normal value. haematoxylin and eosin stained slides pr...

mumps infection is endemic in iran. our objective was to evaluate the presence of anti mumps antibodies ( igm & igg) in cerebrospinal fluid in mumps meningoencephalitic children. a prospective/cross-sectional study was performed in tehran, iran (2003 to 2004) and serum anti mumps antibodies (igm) were detected (quantitive; elisa) in meningoencephaltis patients. specific anti mumps antibodies (i...

objective cerebrospinal fluid (csf), its secretion, circulation and absorption have been the subject of recent researches. there is a general agreement that the main site of csf secretion is in the choroids plexus. however, the main absorption site is controversial. some believe that arachnoid granulations are the principle sites of csf absorption. in this study, different locations of csf abso...

BACKGROUND AND PURPOSE Shunt infection represents a particularly morbid condition, which can also result in mortality. In order to decrease the high morbidity and mortality rates, prevention is an essential step. The purpose of this study was to compare the prophylactic use of ceftriaxone and trimethoprim-sulfamethoxazole (SXT) for the prevention of ventriculoperitoneal (VP) shunt infection. ...

BACKGROUND Normal pressure hydrocephalus (NPH) is considered to be a treatable form of dementia, because cerebrospinal fluid (CSF) shunting can lessen symptoms. However, neuroimaging has failed to predict when shunting will be effective. OBJECTIVE To investigate whether 1H (proton) magnetic resonance (MR) spectroscopy could predict functional outcome in patients after shunting. METHODS Neur...