نتایج جستجو برای: chemoradiotherapy

تعداد نتایج: 9965  

2017
Erhan Akgun Serdar Ozkok Mevlut Tekin Tayfun Yoldas Cemil Caliskan Timur Kose Bulent Karabulut Murat Sezak Nevra Elmas Omer Ozutemiz

BACKGROUND There are only two prospective, randomized studies comparing preoperative long-term chemoradiotherapy and postoperative chemoradiotherapy in locally advanced rectal cancer (LARC); however, conflicting results in terms of locoregional recurrence (LR) and survival rates have been reported. This prospective study aims to compare the effects of preoperative versus postoperative chemoradi...

Journal: :The New England journal of medicine 2012
P van Hagen M C C M Hulshof J J B van Lanschot E W Steyerberg M I van Berge Henegouwen B P L Wijnhoven D J Richel G A P Nieuwenhuijzen G A P Hospers J J Bonenkamp M A Cuesta R J B Blaisse O R C Busch F J W ten Kate G-J Creemers C J A Punt J T M Plukker H M W Verheul E J Spillenaar Bilgen H van Dekken M J C van der Sangen T Rozema K Biermann J C Beukema A H M Piet C M van Rij J G Reinders H W Tilanus A van der Gaast

BACKGROUND The role of neoadjuvant chemoradiotherapy in the treatment of patients with esophageal or esophagogastric-junction cancer is not well established. We compared chemoradiotherapy followed by surgery with surgery alone in this patient population. METHODS We randomly assigned patients with resectable tumors to receive surgery alone or weekly administration of carboplatin (doses titrate...

Journal: :iranian red crescent medical journal 0
fatemeh homaei shandiz research center of solid tumor treatment, ghaem hospital, mashhad university of medical sciences, mashhad, ir iran sima kadkhodayan research center of women’s health, ghaem hospital, mashhad university of medical sciences, mashhad, ir iran; research center of women’s health, ghaem hospital, mashhad university of medical sciences, mashhad, ir iran. tel: +98-5118012477, fax: +98-5118430569 malihe hsanzade mofrad research center of women’s health, ghaem hospital, mashhad university of medical sciences, mashhad, ir iran zohre yousefi roodsari research center of women’s health, ghaem hospital, mashhad university of medical sciences, mashhad, ir iran noorieh sharifi sistani research center of solid tumor treatment, ghaem hospital, mashhad university of medical sciences, mashhad, ir iran majid nabizadeh marvast mashhad university of medical sciences, mashhad, ir iran

conclusions optimal cytoreductive surgery and chemotherapy may be the best treatment in mmmt but more discussion and experiences are needed regarding the effectiveness of radiotherapy. introduction malignant mixed mullerian tumor (mmmt) is a very rare tumor, accounting for less than 1% of all ovarian cancers. case presentation we present a 64-year-old woman with stage iii mmmt of ovary that was...

C.C. Wu, C.H. Liu, C.L. Lai, C.W. Hsiao, M.J. Lai, S.W. Jao,

Background: This study assessed the optimal timing of computed tomography for detection of metastatic disease in locoregional lymph nodes in patients with rectal cancer who have undergone chemoradiotherapy. Materials and Methods: This observational retrospective study was performed in a single institution. All patients with locally advanced rectal cancer treated with chemoradiotherapy, followed...

J.T. Koizumi, K. Mitsudo, K. Osawa, M. Hirota, M. Iida, M. Kioi, N. Ohashi, S. Minamiyama, S. Oguri, T. Iwai, T. Ohya, Y. Hayashi,

Background: The aim of this retrospective study was to evaluate the therapeutic outcomes and organ preservation in patients with squamous cell carcinoma of the buccal mucosa treated with radiotherapy and retrograde superselective intra-arterial chemotherapy. Materials and Methods: Between April 2006 and March 2016, 28 patients (3 with stage II; 8 with stage III; and 17 with stage IV) with squam...

2017
Zhanzhan Li Yanyan Li Shipeng Yan Jun Fu Qin Zhou Xinqiong Huang Liangfang Shen

Background The potential benefits and possible risks associated with combined nimotuzumab and concurrent chemoradiotherapy in patients with advanced nasopharyngeal carcinoma (NPC) have yet to be determined. Methods The databases PubMed, Web of Science, China National Knowledge Infrastructure, and Wanfang were systematically searched through February 2017 for studies comparing combined nimotuz...

2017
David Buka Josef Dvorak Veronika Sitorova Igor Sirak Rene Voboril Bohuslav Melichar Igor Richter

AIM OF THE STUDY The aim was to examine the effects of neoadjuvant chemoradiotherapy on VEGF expression in patients with locally advanced rectal cancer. MATERIALS AND METHODS A total of 53 patients with locally advanced rectal cancer were retrospectively studied. Neoadjuvant treatment comprised external beam radiation (50.4 Gy/28 fractions) with continuous infusion of 5-fluorouracil. Four to ...

2017
Mei-Juan Wang Chao Li Yue Sun Fu-Jun Shen Chun-Bin Wang

The prognostic effect of chemoradiotherapy in gastric cancer has been evaluated for decades while the results are still in debate and heterogeneous. We thus comprehensively updated the evidence through systematic review and meta-analysis to evaluate chemoradiotherapy in gastric cancer to determine its effect. Pubmed, EMBASE, and Cochrane Library from the earliest possible year to April 2017 wer...

2011
Takashi Yasuda Hiroshige Chiba Takafumi Satomi Akira Matsuo Tadayoshi Kaneko Daichi Chikazu Hironobu Miyamatsu

OBJECTIVES To assess the efficacy and safety of rebamipide in preventing chemoradiotherapy-induced oral mucositis in patients with oral cancer. MATERIAL AND METHODS Patients with oral cancer treated with chemoradiotherapy (daily radiotherapy plus docetaxel hydrate once a week) were enrolled for this study. They were assigned in a double-blind fashion to receive either rebamipide gargle or pla...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Brad M Unryn Desiree Hao Stefan Glück Karl T Riabowol

PURPOSE Chronic viral infection and combinations of chemotherapeutic drugs have been reported to accelerate telomere erosion. Here, we asked if chemoradiotherapy, using the single agent cisplatin, would accelerate telomere loss in head and neck cancer patients, and whether loss was linked to smoking status, age, gender, or stage of disease at diagnosis. EXPERIMENTAL DESIGN Blood samples were ...

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