Purpose The primary aim is to compare the change in serum 25OHD concentration between three forms of supplemental vitamin D3: a lipid-emulsified form administered in a sesame oil base, a non-emulsified chewable tablet, and a non-emulsified form administered to 25-hydroxycholecalciferol (25-OHD) insufficient <33ng/ml (75 nmol/ml) patients. The secondary aim is to compare the proportion of partic...

1. Summary statement of the proposal for inclusion, change or deletion Phenytoin base (as EpanutinR) is available as 50mg chewable tablets and an oral suspension of strength 30mg/5ml, and are proposed for addition to the Model List of Essential Medicines, for use in the management of epilepsy in children. It is at least as effective as carbamazepine, phenobarbitone and sodium valproate in the m...

UNLABELLED Leukotriene modifiers (receptor antagonist and biosynthesis inhibitor) represent the first mediator specific therapeutic option for asthma. Montelukast, a leukotriene receptor antagonist is the only such agent approved for use in pediatric patients. Montelukast modifies action of leukotrienes, which are the most potent bronchoconstrictors, by blocking Cysteinyl leukotriene receptors....

Chewable ferrous fumarate tablet is the best iron dosage form for children due to better compliance and lower teeth staining compared to the oral drop. Because of the different desirable properties of chewable tablets and the opposing effects of fillers on them, the mathematical experimental design was used as the formulation approach. Different series of formulations based on single filler (La...

Background: Vitamin D hasa vital starring role in bone metabolism which also promotes the absorption of calcium intestine. Thus, adequate level vitamin is critical importance. Methods:A prospective, randomized, comparative, parallel-group study evaluated effectiveness, safety and tolerability three D3 products patients with deficiency or insufficiency. These included soft gelatin capsule, granu...

AbstractGanyong contains high starch (carbohydrates) which can be used as a binder in tablet formulations. Chewable tablets are intended for people who have difficulty swallowing medicine. One of the chewable preparations is an antacid preparation. Moringa leaves contain substances that useful gastroprotection, anti-ulcer, and antioxidants. This study aims to evaluate use canna ethanol extract ...

Plasma coenzyme Q10 (CoQ10) response to oral ingestion of various CoQ10 formulations was examined. Both total plasma CoQ10 and net increase over baseline CoQ10 concentrations show a gradual increase with increasing doses of CoQ10. Plasma CoQ10 concentrations plateau at a dose of 2400 mg using one specific chewable tablet formulation. The efficiency of absorption decreases as the dose increases....