Brain cancer is one of the most prevalent childhood cancers in the United States and Canada, second only to leukemia [1, 2]. The overall incidence of childhood brain tumors, the most common solid tumor in children, rose from 2.3 cases per 100,000 in 1975 to 3.0 cases per 100,000 in 1998 in the United States [1]. Similar rates were also seen in Canada [2]. One concern is that the elevated risk o...

BACKGROUND Dermatologists, paediatricians, and general practitioners are often consulted by worried parents for the evaluation of a cutaneous tumor. METHODS Selective literature review. RESULTS Only 1-2% of skin tumors excised in children turn out to be malignant when examined histologically. Warning signs of malignancy include rapid growth, firm consistency, diameter exceeding 3 cm, ulcera...

Central nervous system (CNS) cancers are the second most frequent malignancy in childhood and the most common solid tumor in this age group. In recent years, significant advances in surgery, radiotherapy, and chemotherapy have favorably impacted survival for children with these tumors. However, a significant proportion of patients with CNS tumors suffer progress disease despite such treatment. ...