Nephrotic syndrome is a common renal disorder in children, characterized by nephrotic range proteinuria, hypoalbuminemia, hyperlipidemia, and edema. The most common type is primary (idiopathic) associated with minimal change disease, which responds very well to steroid therapy and has a good long-term prognosis. Other causes, clinical presentation, laboratory findings, and management are discus...

This thesis is based on the following original publications, which are referred to in the text by Roman numerals. pharmacodynamics of pravastatin in children with familial hypercholesterolemia. Efficacy and safety of pravastatin in children and adolescents with heterozygous familial hypercholesterolemia: a prospective clinical follow-up study. noncholesterol sterols in children with familial hy...

Pediatric Nephrotic Syndrome is a renal disorder of children, characterized by nephrotic range proteinuria, hypoalbuminemia, hyperlipidemia and edema. The most common type is primary (idiopathic) associated with minimal change disease, which responds very well to steroid therapy and has a good long-term prognosis. Other causes, clinical presentation, laboratory findings and management are discu...

introduction: hyperlipidemia is a major cardiovascular risk factor. this survey has been performed to determine the prevalence of hyperlipidemia in the 17th zone of tehran. methods: 1573 individuals 25-64 aged were recruited from the inhabitants of the 17th zone of tehran through one stage cluster sampling. standard questionnaires were filled out for all of the participants. lipid profile was c...

Cardiovascular disease is the leading cause of death in the United States. There is substantial evidence that the atherosclerotic process begins in childhood, with the presence of fatty streaks in the aorta by 10 years of age and in the coronary arteries by 20 years of age.1 Atherosclerotic lesions, which occur in up to 38 percent of persons with multiple risk factors, are more common in young ...

Patients and methods From 2007 to 2013, 30 children with primary hyperlipidemia were recruited and were treated with diet and/or lipid-lowering drug therapy at the National Hospital of Pediatrics, Hanoi, Vietnam. Clinical symptoms and biochemical finding, outcome of treatment were studied. Results: Among 30 cases from 28 families, 8 patients were mixed hyperlipidemia (MHL), 13 patients were hyp...

variations in phosphatidate phosphohydrolase (pap) activity and triacylglycerol concentration were measured in pregnant and hormone-treated non-pregnant female rats. pap activity in adipose tissue was elevated by 61% during pregnancy. the increase in the enzyme activity was paralleled with a rise in serum triacylglycerol concentration (44%). estradiol injecting into non-pregnant rats increased ...

purpose: to evaluate the association between hyperlipidemia with severity of diabetic retinopathy in patients with type i diabetes mellitus referred to the eye clinic at imam khomeini hospital, ahvaz, iran. methods: this observational cross-sectional study included 52 patients with type i diabetes mellitus. fasting blood samples for analysis of serum lipids and hba1c were obtained from all pati...