It is well known that most anticancer drugs commonly show high toxicity to the DNA of tumor cells and exert effects by combining with the DNA or associated enzymes in the nucleus. Most developed drugs are first delivered into the cytoplasm and then transferred to the nucleus through the membrane pores. Sometimes, the transportation of drugs from cytoplasm to nucleus is not efficient and often r...

-Chitosan is natural polysaccharide resembles with glycosaminoglycan of Extra Cellular matrix (ECM), which makes it a promising candidate for wound healing application apart from its excellent biocompatibility and biodegradability. In this study we have formulated various types of chitosan gel by dissolving different concentrations of chitosan powder in 100 ml of 2% acetic acid separately. Elec...

Curcumin, a naturally occurring antioxidant, has various beneficial effects in the treatment of human diseases. However, little information regarding the protection it provides against acute liver injury is available. The present study investigated the protective effects of curcumin against D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced acute liver injury in mice. A total of 40 male ...

The ability of Burkholderia pseudomallei to persist and survive in the environment is a health problem worldwide. Therefore, the antibacterial activities of chitosan against four environmental isolates of B. pseudomallei from soil in Khon Kaen, Thailand, were investigated. Antibacterial activities were assessed by a plate count technique after treatment with 0.2, 0.5, 1, 2 or 5 mg ml-1 chitosan...

The quality attributes and storage life of ‘Jinhwang’ mango fruit can be effectively maintained with 1-methylcyclopropene (1-MCP) application and/or chitosan coating. ‘Jinhwang’ mango fruit was treated with 5 μl l 1-MCP for 12 h, dipped with 0.5 % chitosan, 5 μl l 1-MCP combine with 0.5 % chitosan and untreated (control) then stored at 10C. Mango treated with 1-MCP maintained firmness, sucrose ...

Abstract. Let GL(2,H) be the group of invertible 2 × 2 matrices over the division algebra H of quaternions. GL(2,H) acts on the hyperbolic 5-space as the group of orientation-preserving isometries. Using this action we give an algebraic characterization of the dynamical types of the orientation-preserving isometries of the hyperbolic 5-space. Along the way we also determine the conjugacy classe...

To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentration and volume of 1% w/v TPP solution) had a significant influence on the charac...

objective(s): binary hybrids of chitosan-zeolite have many interesting applications in separation and bacteriostatic activity. materials and methods: template free zsm-5 zeolite was synthesized by hydrothermal method, physical hydrogels of nano chitosan in the colloidal domain were obtained in the absence of toxic organic solvent and then nano chitosan/zsm-5 hybrid composites with nano chitosan...

In this work, chitosan and collagen-chitosan porous scaffolds were produced by the freeze drying method and characterized as potential skin substitutes. Their beneficial effects on soft tissues justify the choice of both collagen and chitosan. Samples were characterized using scanning electron microscope, Fourier Transform InfraRed Spectroscopy (FTIR) and thermogravimetry (TG). The in vitro cyt...

Photodynamic medicine is a novel approach for cancer detection and treatment via different photosensitizers and suitable light source. The 5-Aminolevulinic acid (5-ALA) can be converted into protoporphyrin IX (PpIX), and in cancer cells which serves as a fluorescent probe for tumor detection. In this study, folic acid was conjugated onto chitosan molecules via covalent bond for specific target,...