The effect of two acids (phosphoric and acetic) and their derivatives (hydrogen di(2-ethylhexyl)orthophosphoric, chloroacetic, dichloroacetic, trichloroacetic, and trifluoroacetic acids) on the retention of selected alkaloids on silica gel plates has been investigated. The dependence of the chromatographic behaviour of the alkaloids on mobile phase diluent and on the concentration of the acids ...

The kinetics of the alkylation of the essential sulfhydryl group of papain with chloroacetic acid was studied. The variation of the second order rate constant with pH at 4.5” and 30.5’, r/2 = 0.07, is bell-shaped, with rate constants at a maximum near neutrality, approaching zero at low pH, and approaching a positive minimum at high pH. These profiles are described by a formulation which relate...

The characterization and design of this study new liquid crystals with a V shape compounds containing thiazolidine-2,4-dione 1,3-phenylene as core unite mesophase properties were reported. Preparation chloroacetic acid, water, thiourea to produce [I] in the presence strong hydrochloric acid. 4-hydreoxybenzaldehyde n-alkyl bromide reacted potassium hydroxide create n-alkoxy benzaldehyde., then c...

In this study, a new series of 6-amino-1,3-dimethyluracil derivative with 6-(3-substituted N-benzylidene)-1,3-dimethyl pyrimidine-2,4-dione-6-yl derivatives which were synthesized by using one pot synthesis. The reaction and different aromatic aldehyde in ethanol yielded Schiff bases (1-6). the subsequent step )1-6) 2-mercaptoacetic acid, 2-chloroacetic acid 2-amino acetic acidn Tetrahydrofuran...

A new series of 2-hydrazone-thiazoline-4-ones 3a-d and 2-hydrazone-5arylidene-thiazoline-4-ones 4a-h, 5a-f and 6a-b were synthesized starting from various thiosemicarbazones by the Hantzsch condensation with chloroacetic acid. The newly synthesized compounds were screened for their antimicrobial activity against 4 strains of bacteria: Staphylococcus aureus (ATCC 29213), Bacillus subtilis (ATCC ...

A series of novel bis-thiazolidinone derivatives 3(a-j) have been synthesized by the cyclization thiosemicarbazones 2(a-j) with chloroacetic acid and sodium acetate. The integrated heterocyclic compounds were featured chemical spectroscopic methods such as IR, 1H NMR 13C NMR. All screened for their antimicrobial activity against Gram-positive Gram-negative bacteria Staphylococcus Aureus, Bacill...