BACKGROUND Traditional healers in Ethiopia use a wide range of medicinal plants with antidiarrheal properties. Among these, Croton macrostachyus is one such plant claimed to have an antidiarrheal activity in Ethiopian folklore medicine. Previous studies showed that the crude extract is endowed with the claimed property. The present study was undertaken to further the claim by screening differen...

background and objectives: malaria is a remarkable cause of death in the world. several ways are used by researchers to control or to decrease the detrimental effects of the disease, in which natural insecticides with less malaria vectors resistance and lower environmental damages are considered in last decades.the objective of this study was to assess the larvicidal activity of the whole flowe...

persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in nigeria. hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of p. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in wistar rats to substantiate this claim. the chloroform and met...

Leaves of Catharanthus roseus (L) G. Don (72 kg) were collected from a field grown in the Karachi Uni­ versity campus. The crude alkaloids (134 g) obtained from the alcoholic extract of the air-dried leaves (24 kg) of the plant, were dissolved in chloroform (450 ml) and extracted with pH 3 phosphate buffer (1 1). The chloroform layer was dried (anhydrous Na2S 0 4), concentrated to 1/3 of its or...

The study was carried out to evaluate the anti-diabetes activity of ethanol extract of Centella asiatica (L.) Urban in streptozotocin diabetic rats, to determine the acute and subacute toxicity of the extract in mice and to isolate most active anti-hyperglyceamic fraction of ethanol extract. Diabetes was induced in male Wistar rats by streptozotocin (50mg/kg) injection and anti-diabetes efficac...

OBJECTIVE To investigate the protective effects of hydroalcoholic and its fractions from roots of Hemidesmus indicus on arthritis in in vitro models of rodents. METHODS Preliminary phytochemical analysis and thin-layer chromoatography were performed to analyze constituents of hydroalcoholic extract and its three fraction namely ethyl acetate fraction, chloroform fraction and residual fraction...

A lipid fraction was obtained by extraction with chloroform-methanol (1:1 .v/v) of "the S-precipitate"prepared from whole human saliva by one precipitation.This fraction produced leukocytosis, but not hypocalcemia , in rabbits upon intravenous injection. Saliva-parotin-A purified from the S-precipitate possessed both hypocalcemic and leukocytosis-promoting activities, which remained unaffected ...

The chloroform extract of Ferula persica var. persica roots was found to inhibit red pigment production of Serratia marcescens. A bioguided fractionation study by preparative thin layer chromatography (PTLC) detected a fraction (Rf = 0.71, petroleum ether/EtOAc, 2:1 v/v), which was effective on depigmentation of Serratia marcescens. Using conventional spectroscopy methods, the active fraction w...

The present investigation was designed to study the effect of an active compound isolated from Justicia wynaadensis against multi drug resistant organisms (MDRO's) associated with diabetic patients. The drug resistant pathogens implicated in wound and urinary tract infection of diabetic patients were isolated and identified by molecular sequencing. Solvent-solvent fractionation of crude methano...

Persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in Nigeria. Hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of P. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in Wistar rats to substantiate this claim. The chloroform and met...