Chlorogenic acid exists widely in edible and medicinal plants and acts as an antioxidant. It is known to exert antitumor activity via induction of apoptosis in many human cancer cells. However, its signaling pathway in human leukemia cells still remains unclear. Therefore, we investigated the roles of reactive oxygen species (ROS), mitochondria and caspases during chlorogenic acid-induced apopt...

Using HPLC, the seasonal changes in the phenolic compound content of the leaves of the Gemlik olive cultivar (Olea europaea L) has been investigated with respect to the effects on the alternate bearing of the cultivar. For this purpose, the leaf concentrations of oleuropein, chlorogenic acid, caffeic acid, 3-hydroxycinnamic acid, scopolin and pcoumaric acid were analyzed at 10 day intervals aro...

in chlorogenic acid (5-caffeoylquinic acid) (Fig 1). Coffee, one of the most widely consumed beverages in the world, is the major dietary source of chlorogenic acids. Chlorogenic acid has antioxidant properties as shown by its ability to scavenge various free radicals when tested in vitro (3-5). Moreover, chlorogenic acid reduces glucose uptake by favouring the dissipation of the Na+ electroche...

artichoke (cynara scolymus l) belongs to asteraceae. a factorial experiment based on the randomized complete block design with three replications was carried using depths of root available water (raw) and sowing time (st) as treatments. leaf length and width, number of leaves per plant and the biomass yield were recorded before laboratory analysis. in laboratory total phenols, total flavonoids,...

A chlorogenic acid sensor based on a chitosan (CS) and multi-walled carbon nanotubes (MWCNTs) modified glassy carbon electrode (GCE) was fabricated via a layer-by-layer (LBL) self-assembly method. The prepared electrode exhibited excellent catalytic performance for chlorogenic redox reactions compared to the bare GCE. The effects of the number assembly layers, scan rate, pH of the supporting el...

Background and Objectives: Chlorogenic acid, a natural polyphenolic compound has been reported to possess neuroprotective and antioxidant activities, but the effect of chlorogenic acid on orofacial dyskinesia has not been explored till date, so the aim of the present study was to investigate the effect of chlorogenic acid on reserpine-induced orofacial dyskinesia in Wistar male albino rats. Met...

Scarlet (Solanum aethiopicum) and gboma (S. macrocarpon) eggplants are important vegetables in Sub-Saharan Africa. Few studies have been made on these crops regarding the diversity of phenolic content and their biological activity. We have studied the reducing activity, the chlorogenic acid and other phenolic acid contents in a collection of 56 accessions of scarlet eggplant, including the four...

Chlorogenic acid, the depside formed by the condensation of caffeic and quinic acids, was first obtained in crystalline form by Gorter (1909) from green coffee beans, although considerably earlier Ludwig & Kromeyer (1854) had noted the presence in the seeds of the sunflower of a compound which was undoubtedly chlorogenic acid. The acid was first thought to be a glycoside of caffeic acid, but Go...

Three phenylpropanoids (ferulic acid, chlorogenic acid, and caffeic acid) are simultaneously separated and determined within 13 min by a new capillary electrophoresis method using 15 mmol/L sodium borate (pH 8.71) as run buffer. The optimum conditions for the separation as well as the analytical characteristics, such as the calibration graph and limit of detection (LOD) for the determination of...

Chlorogenic acid (5-O-caffeoylquinic acid) is a phenolic compound from thehydroxycinnamic acid family. This polyphenol possesses many health-promoting properties, mostof them related to the treatment of metabolic syndrome, including anti-oxidant, anti-inflammatory,antilipidemic, antidiabetic, and antihypertensive activities. The first part of this review will discussthe role of chlorogenic acid...