Objectives: Psychotropic drug use in the elderly with chronic schizophrenia is an important issue in the field of psychiatry. The main goal of this study was to clarify the pattern of such drug use in these patients, in order to consider such therapy plan and focus on its cost attributing measures, for a more reasonable quality of care program. Methods: In this descriptive study, participant...

The aim of the present experiments was to clarify the influence of chlorpromazine on 5-hydroxytryptamine (5HT) in mouse brain. It was shown earlier (Bartlet, 1960) that the injection of iproniazid into mice produced an accumulation of cerebral 5HT, and that the rate of accumulation of the amine was reduced by chlorpromazine. It was suggested that chlorpromazine reduced the rate of formation of ...

In this study, on the combination of chlorpromazine with two aromatic rings, halogens are attached to the rings, and changes in the angles and lengths of the ipsos are calculated. Calculations show that by changing the halogen based on the amount of electronegativity, the magnitude and variation of the angular lengths The lengths of the links also change in the following order. The angles of th...

Interaction of Chlorpromazine with tricyclic antidepressants was investigated in twenty schizophrenic patients after their concurrent administration. A significant increase in serum chlorpromazine concentration was observed when administered in combination with both amitriptyline and imipramine with chlorpromazine. If combined therapy is indicated, the dose of chlorpromazine should be reduced o...

In the present study, magnetic core-shell manganese ferrite nanoparticles (MCMNP) were synthesized and used for construction of a magnetic core-shell manganese ferrite nanoparticles modified screen-printed carbon electrode (MCSNP-SPCE). Cyclic voltammetry was used to study the electrochemical behavior of chlorpromazine (CPZ) and its determination was conducted by applying square wave voltammetr...

the effects of chronic administration of lithium, on acute toxicity of chlorpromazine (cpz) in male albino mice was studied and the ldso values were determined from dose-probit curves. tfie results showed that in lithium pretrealed animals (anmials consumed drinking water containing 600mg/l lithium chloride for 10 days) the ld50 value (the dose corresponding to probit 5) of cpz increased signif...

objectives: the aim of this study was to investigate the prevalence and its determinants of antipsychotic use in patients with psychiatric disorders. materials and methods: this study was on patients with psychiatric disorder that have discharged from the hospital. we have assessed all patients with psychiatric interview and evaluation of their psychiatric documentations. results: 90.7% of all ...