As part of the National Human Exposure Assessment Survey (NHEXAS) in Maryland, we collected indoor air, carpet dust, exterior soil, and duplicate diet samples from a stratified random sample of 80 individuals to evaluate aggregate daily exposure, contributions of specific pathways of exposure, and temporal variation in exposure to chlorpyrifos. We collected samples from each participant in up t...

Chlorpyrifos is one of the mostly used organophosphates insecticides, has a major toxic effect in mammalian rat’s reproductive system. The ancient Indian herbal formulation, Emblica offcinalis plays a major role to subvert many diseases in human body. Through a preliminary study, we have tried to establish the ameliorative properties of Emblica offcinalis with respect to reproductive rejuvenati...

AIMS To determine whether chronic occupational exposure to chlorpyrifos at levels associated with various aspects of manufacturing produced a clinically evident or subclinical peripheral neuropathy. METHODS Clinical and quantitative nerve conduction study (NCS) examinations were performed on two occasions on chlorpyrifos manufacturing workers who had measurable chlorpyrifos exposure and a ref...

Aerially applied adherent corn flour granules containing 1% malathion were more often as, or more, effective than 15% chlorpyrifos (Lorsban 15G) granules in controlling caterpillars and sap beetles in high amylose corn in 1997 than 1996. Use of malathion granules corresponding closely in size to chlorpyrifos granules in the second year of the study apparently increased relative efficacy. Signif...

The residue behavior of chlorpyrifos, which is one of the extensively used insecticides all around the world, in six vegetable crops was assessed under greenhouse conditions. Each of the vegetables was subjected to a foliar treatment with chlorpyrifos. Two analytical methods were developed using gas chromatography equipped with a micro-ECD detector (LOQ = 0.05 mg kg(-1)) and liquid chromatograp...

Studies of human cases of self-inflicted poisoning suggest that chlorpyrifos oxon reacts not only with acetylcholinesterase and butyrylcholinesterase but also with other blood proteins. A favored candidate is albumin because in vitro and animal studies have identified tyrosine 411 of albumin as a site covalently modified by organophosphorus poisons. Our goal was to test this proposal in humans ...

This study investigated the effect of chlorpyrifos on thoracic aorta and on the level of NO in plasma and aorta. The effect of chlorpyrifos on thoracic aorta in organ bath was determined in 10 rats. Another 45 rats were assigned to 3 groups with 15 rats each: control group 1 received distilled water, control group 2 was given corn oil, and the last group was given 13.5 mg/kg chlorpyrifos dissol...

Chlorpyrifos is a typical organophosphate pesticide and is among the most widely used worldwide. The objective of the present investigation was to assess the effect of chlorpyrifos exposure on glutathione S-transferase in Locusta migratoria. In the present study, chlorpyrifos (0.1, 0.2, and 0.4mgg(-1) body weight) was topically applied in the abdomen of locusts. The GST activity, mRNA levels of...

background: chlorpyrifos is an organophosphate pesticide that elicits broad-spectrum insecticidal activity against a number of important arthropod pests. determining the insecticides’ toxicity to amphibians can give us a better understanding regarding the role of toxicants in amphibian declines. this information would be beneficial to assess their ecological relevance at environmental concentra...

Children appear to be more susceptible to chlorpyrifos poisoning than adults, and are often exposed to more residues. The U.S. Environmental Protection Agency estimates children consume (after adjusting for their size) between 2 and 2.5 times as much chlorpyrifos on their food as do adults. When houses are treated with chlorpyrifos, carpets can serve as a source of chlorpyrifos vapors when resi...