Cholelithiasis is one of the major health problems around world. The prevalence cholelithiasis varies by country. ethnicity people and geographical location a country has huge role in gallstone disease. etiology gallstones not well understood. most important predisposition factor formation supersaturation cholesterol, hypomotility gallbladder, excess bilirubin. Gallstones risk factors are multi...

Cholelithiasis in infants and children is rare. There are very few reports of cholelithiasis in infants with Down’s syndrome. Here we are reporting two cases of Down’s syndrome aged 3 months and 6 months respectively in whom cholelithiasis was detected. One of the babies had nephrolithiasis also. Down’s syndrome patients are at an increased risk of developing lithiasis and should be monitored t...

INTRODUCTION Extended immunosuppressive treatment in patients after heart transplantation modifies etiopathogenesis and occurrence of many diseases in this population. The aim of the present study was to evaluate the frequency and to define risk factors for cholelithiasis after heart transplantation (HTX). MATERIAL AND METHODS The study population consisted of 176 subjects. Of them, 24 patien...

background recent studies regarding the effect of hydroxyurea (hu) in thalassemia have revealed favorable effects on the reduction of ineffective erythropoiesis. objectives the aim of the current study was to evaluate whether or not hu can have an effect on the gallstone formation rate in patients with beta-thalassemia intermedia (bti). patients and methods in this case control cross-sectional ...

A 40-year old woman presented with symptomatic intrahepatic gallstones in one liver segment only four years after cholecystectomy for cholelithiasis. Multiple small, yellow and round calculi were completely removed from the intrahepatic bile ducts via ERCP. The young age of the patient, recurrence of gallstones after cholecystectomy and intrahepatic gallstones suggested a subtype of the low-pho...

Leptin and its receptor play several physiological roles in the canine gallbladder, and the dysregulation of leptin might play a role in the pathogenesis of gallbladder diseases such as gallbladder mucocele. Previous studies revealed a positive association between hyperlipidemia and gallstones in humans. However, the latter is still unclear in dogs with cholelithiasis. In this study, we examine...

AIM To evaluate the role of laparoscopic cholecystectomy (LC) in the management of cholelithiasis in children. MATERIALS AND METHODS A retrospective review of our experience with LC for cholelithiasis at our institution, between April 2006 and March 2009 was done. Data points reviewed included patient demographics, clinical history, haematological investigations, imaging studies, operative te...