A 42-year-old woman with choriocarcinoma required emergency pulmonary embolectomy under cardiopulmonary bypass. After diagnosis of choriocarcinoma was confirmed by examination of tumor emboli specimens, the patient was treated and had complete remission by chemotherapy over a 6-month period. Although rare, choriocarcinoma should be considered in the differential diagnosis of fertile women prese...

•We report on the medical treatment and outcomes of choriocarcinoma in Hispanic postmenopausal women.•A diagnosis of choriocarcinoma should be considered in older women with elevated serum β-hCG levels.•The unadjusted incidence of choriocarcinoma was calculated using data from the Texas Cancer Registry.

Pure ovarian choriocarcinoma can be gestational or nongestational in origin. Nongestational choriocarcinoma of the ovary is extremely rare, and its diagnosis is very difficult during the reproductive years. We present a case of a 33-year-old woman diagnosed with pure nongestational ovarian choriocarcinoma. Following surgery, multiple courses of a chemotherapy regimen of etoposide, methotrexate,...

BACKGROUND Primary non-gestational uterine cervical choriocarcinoma is very unusual and although it has been hypothesized that it can arise by metaplastic transformation of cervical epithelium, solid evidence has been lacking. CASE Primary non-gestational uterine cervical choriocarcinoma was diagnosed in a 47-year-old, woman undergoing tubal resection 17 years previously. A histologically- an...

Background: Chorionic carcinoma is a highly malignant gynecological tumor, frequently originating from trophoblastic cells in the uterus after fertilization. Early erosion releases cancerous cells into the circulation to invade surrounding organs without primary symptoms and signs. Methods: One case of choriocarcinoma sellar region metastasis was analyzed, utilizing clinical data, MRI and patho...

Choriocarcinoma is a highly malignant tumor that can arise from trophoblasts of any type of gestational event but most often from complete hydatidiform mole. IGF-II plays a fundamental role in placental development and may play a role in gestational trophoblastic diseases. Several studies have shown that IGF-II is expressed at high levels in hydatidiform moles and choriocarcinoma tissues; howev...

a 33-year-old female presented with intermittent abdominal pain and severe attacks of lower gastrointestinal (gi) bleeding since 2 weeks. she has had history of irregular menses in last 3 months. in the labeled rbc-scan study, the bleeding site was detected in left upper quadrant (luq). in surgery, a tumor with the diameter of 2ã—1cm in a 65 cm distance of ligament of trietz was detected. in pa...

INTRODUCTION Diverse sequelae of central nervous system metastasis of choriocarcinoma have been reported, including infarction, intra or extra axial hemorrhages, aneurysm formation and carotid-cavernous fistula. Here we report a case of subdural hematoma as the first presentation of choriocarcinoma. CASE PRESENTATION The patient is a 34-year-old woman whose initial presentation of widely meta...

Choriocarcinoma is an aggressive trophoblastic neoplasm; its origin could be gestational or non-gestational.  Most are gestational, which means they arise from pregnancy, may abnormal normal. This review includes the published literature about choriocarcinoma's prevalence and risk factors. The researchers searched Science Direct, PubMed, EBSCO, Web of Science, Cochrane library, Scopus....