PURPOSE To investigate the effect of Fas and Fas ligand (FasL) deficiency on the development of herpes stromal keratitis and on the von Szily model of herpes retinitis in C57BL/6 mice, which are ordinarily resistant to development of both of these herpetic diseases. METHODS Anterior chamber inoculation of the right eye of each mouse with various titers of HSV-1 (KOS strain) was performed. Bot...

Chorioretinal involvement, frequently asymptomatic and self-limited, is common in patients with West Nile virus (WNV) infection associated with neurologic illness. A bilateral multifocal chorioretinitis, with typical clinical and fluorescein angiographic features, is the most common finding, but numerous other ocular manifestations can occur. Diabetes mellitus appears to be a potential risk fac...

A 63-year-old female with candidemia following necrotizing pancreatitis developed clinical signs of chorioretinitis and underwent the systemic administration of voriconazole, after which anterior chamber inflammation and multiple, white, fluffy, chorioretinal lesions, under 1mm in diameter, were gradually resolved and visual acuity improved. We report the first Korean case of candida chorioreti...

and in the mother affords very strong evidence in favour of this disease as the cause of the macular foci and thereby-through impaired vision-indirectly of the strabismus. Despite the pronounced concordance the strabismus must in these patients be considered as exogenously conditioned. We were able to find two reports in the literature of monozygotic twins suffering from toxoplasmosis and lesio...

To report a rare case of bilateral granulomatous chorioretinitis complicated by bilateral peripapillary choroidal neovascular membranes. This is the first reported case in Australia where intravitreal injections of anti-vascular endothelial growth factor ranibizumab were used to successfully treat choroidal neovascular membrane caused by granulomatous chorioretinitis. This is also the first rep...