1. When pigs were fed diets deficient in pyridoxine or pantothenic acid, ataxia developed and lesions were found in the sensory neuron. 2. The morphological pattern of the lesions differed in the early stages of the two deficient states. Degeneration of the peripheral process of the sensory neuron was the initial and most prominent feature in pyridoxine deficiency. Chromatolysis was the first e...

It is well known that the nerve cell shows the chromatolysis after the section of the axone, and there is a considerable amount of literature upon the subject. But we have only some few reports conscerning the structural changes of the nerve cells which occurs under the influence of a powerful electric current. Wendt (Strand. Archiv f. Phisiol. XI) examined the spinal ganglion of frogs by means...

Manometric determinations of cytochrome oxidase activity were carried out on grey matter from the thalamus and anterior horn of cats and monkeys under various experimental conditions. The thalamus of the cat was studied following the degeneration of virtually all the thalamic neurons secondary to decortication. In comparing the deneuronated thalamus with the normal one, it was found that approx...

STUDY DESIGN The aim of this study is to investigate changes in lumbar motor neurons induced by mechanical nerve root compression using an in vivo model. This study is to investigate the changes of lumbar motor neuron induced by mechanical nerve root compression using in vivo model. OBJECTIVES The effect of axonal flow disturbance induced by nerve root compression was determined in lumbar mot...

cular dystrophy (OPMD) involving 6 members over 4 generations is described. The patient first noted drooping of his eyelids at the age of 65. Dysphagia and dysarthria occurred soon thereafter. At age 78, impairment of gait developed and progressive wasting occurred in the limbs with an initial distal distribution. Electromyography of several limb muscles displayed a mixed myopathic and neurogen...

Studies on the neuroprotective and promyelinating effects of progesterone in the nervous system are of great interest due to their potential clinical connotations. In peripheral neuropathies, progesterone and reduced derivatives promote remyelination, axonal regeneration and the recovery of function. In traumatic brain injury (TBI), progesterone has the ability to reduce edema and inflammatory ...

Significant changes in the neurons of some of the brain stem nuclei were found following experimentally induced brain concussion (Windle, Groat, and Fox, (5), Windle, Groat, and Magoun, (fi)). A chromatolysis was found in the neurons of the reticular formation of the medulla oblongata, in the lateral vestibular nucleus (Deiter's nucleus), the red nucleus, the nucleus of the spinal trigeminal tr...