background: idiopathic thrombocytopenic purpura is an autoimmune blood disorder in which platelet destruction is mediated by anti-platelet antibodies. there are two forms of itp: acute and chronic. the aim of the present study was to evaluate the clinical variables in adult patients with acute itp in west of iran. patients and methods: medical records of adult patients with diagnosis of acute i...

Aim: Immune thrombocytopenia (ITP) is the most common acquired bleeding disorder in childhood. The study aimed to assess demographic and clinical characteristics, treatment responses evaluate their effects on chronicity pediatric ITP cases.
 Material Methods: Primary patients aged 1 month 18 years, who were diagnosed followed up Pediatrics Clinic of Tokat Gaziosmanpaşa University Hospital ...

OBJECTIVE To find the pattern of idiopathic thrombocytopenic purpura (ITP) (acute/chronic) and to describe presenting features and clinical characteristics of the disease in children below 14 years of age in a newly developed Arabian society. METHODS This retrospective, descriptive study was carried out at the Pediatric Department of the Hamad General Hospital, Hamad Medical Corporation, Qata...

PURPOSE This study aimed to evaluate the clinical course of childhood immune thrombocytopenia (ITP) and to assess the risk factors for developing chronic ITP. METHODS The records of 64 children diagnosed with ITP from November 2005 and December 2014 at single center were retrospectively analyzed. RESULTS The median age at diagnosis and the median platelet count were 1 year (range, 1 month t...

OBJECTIVE Immune thrombocytopenic purpura (ITP) is the most common cause of acquired thrombocytopenia in children. The objective of this study was to evaluate the presenting features, variation in the clinical courses, initial response rate to therapy, and long-term outcome in patients with ITP. METHODS Three hundred and fifty out of 491 newly diagnosed patients with ITP between the initial d...

OBJECTIVE To increase our understanding of the etiology of idiopathic thrombocytopenic purpura (ITP) some cytokine gene polymorphisms were analyzed for susceptibility to the disease. The aim of this study was to investigate the role of tumor necrosis factor-alpha (TNF-α) -308 G/A and transforming growth factor-beta 1 (TGF-β1) -915 G/C polymorphisms in the development and clinical progression of...

Abstract Objective Immune thrombocytopenic purpura (ITP) manifests as an easy bruising or extravasation of blood from capillaries into skin and mucous membranes. The characteristics of acute ITP in infants have rarely been described. In order to better understand acute ITP in infants, the characteristics of the disease at this age group was investigated. Material and Methods The present des...

Eradication of Helicobacter pylori may lead to improvement of chronic immune thrombocytopenic purpura (ITP), although its efficacy over time is uncertain. We report the results of H pylori screening and eradication in 75 consecutive adult patients with ITP. We also used molecular methods to investigate lymphocyte clonality and H pylori genotypes in the gastric biopsies from 10 H pylori-positive...

Idiopathic thrombocytopenic purpura (ITP) is the most common acquired bleeding disorder in childhood. ITP is characterized by a lo� circulating platelet count caused principally by destruction of antibody-coated platelets in the reticuloendothelial system. It can be classified into t�o major forms, acute and chronic. Acute ITP is usually a benign self-limiting condition �ith a high probability ...