Cutaneous leishmaniasis is an endemic disease in Iran and there is no curative treatment. The disfiguring scar that remains after it subsides is a major psychologic and emotional problem in these patients. Chronic leishmaniasis is a rare form of this malady which is seen in 5-7 percent of cases. In this article we report a 46-year-old man who was refered to us for a large leishmaniasis lesion c...

In the present study, anti-Leishmania immunoglobulin G (IgG) avidity was used to estimate the approximate time of disease manifestation. Significant differences (P < 0.0001) were found between the levels of anti-rKE-16 IgG avidity in leishmaniasis patients with recent and chronic diseases. More than 76% of patients with an illness duration of less than 6 months had avidity of less than 70%, 94%...

Three cases of visceral leishmaniasis with oral manifestations are described. Two of these cases presented with chronic non-healing ulcers. The third case presented with characteristic erythematous, swollen and bleeding gingiva. The clinical appearance of both forms of presentation is discussed, and the importance of including oral leishmaniasis in the differential diagnosis of similar oral les...

We report a case of visceral leishmaniasis (VL) in an immunocompetent native from non-endemic region of India that presented with chronic diarrhoea. VL was not a differential diagnosis and was unexpectedly diagnosed as intestinal leishmaniasis through the identification of the Leishman-Donovan (LD) bodies in duodenal and colonic mucosa. The patient expired before receiving antileishmanial therapy.

Leishmaniasis is a parasitic disease caused by Leishmania species and is classified into three forms; cutaneous, mucocutaneous, and visceral. The eyelid is a rare site involved by leishmaniasis and only makes up 2.5% of cases with cutaneous leishmaniasis (CL). Although CL can affect both upper and lower lids on either their outer or inner aspects, the lateral canthus is most often affected. The...

Lupoid leishmaniasis, a clinical form of cutaneous leishmaniasis, was described by Christopherson in 1923 [1]. It is a chronic condition that typically follows acute cutaneous leishmaniasis infection. In this clinical form, 1 to 2 years after healing of the acute lesion, new papules and nodules appear at the margin of the remaining scar. The papules have a granulomatous, lupoid appearance and a...

Leishmaniasis comprises a group of diseases caused by a protozoan parasite belonging to the genus Leishmania and transmitted by the bite of infected female sand flies. Leishmaniasis is endemic in 88 countries and causes significant morbidity and mortality worldwide. Phenomena such as globalization and human migration, as well as the increased volume of international travel have extended its pre...

Clinical manifestations of leishmaniasis are diverse and related to the infecting species, its relationship with the environment and the host immune response. A case of late Andean cutaneous leishmaniasis with extensive manifestation is presented. The case was confirmed through microbiological and immunological studies; identification was performed by cytochrome b gene sequencing and the specie...

Visceral leishmaniasis (VL) is a chronic debilitating disease prevalent in tropical and subtropical regions, caused by protozoan parasites of the genus Leishmania. Annually, it approximated occurrence 0.2 to 0.4 million novel cases worldwide. The cast film method was used prepared cationic mannosylated liposomes. surface Amphotericin B (Amp B)-bearing multilamellar liposomes covalently coupled ...