A 31-year-old woman was referred with a painful mass in the left breast that was initially treated with antibiotics. Three weeks later, the mass had increased and polyarthritis and erythema nodosum had developed in both legs. A core needle biopsy led to a diagnosis of granulomatous mastitis with arthritis and erythema nodosum. Low-dose prednisolone (10 mg) rapidly improved the arthritis and the...

S. aureus is a major aetiological agent of ruminant mastitis worldwide. The chronic nature of S. aureus mastitis makes it difficult to cure and prone to resurgence. In order to identify the bacterial factors involved in this chronicity, Newbould 305 (N305), a strain that can reproducibly induce mild and chronic mastitis in an experimental setting, was characterized in depth. We employed genomic...

Currently, somatic cell count (SCC) and bacterial culture are considered as the gold standard of detecting subclinical Mastitis. Mastitis leads to proliferation of lymphocytes in the supramammary lymph nodes and subsequent enlargement of ipsilateral lymph node. Ultrasonography can be used to survey these changes. A portable ultrasound machine with a 2-5 MHz convex transducer was used to identif...

Chronic granulomatous mastitis is known as a benign and relatively rare disorder that is often difficult to differentiate from breast carcinoma. We highlight the case of a 34-year-old woman who had recurrent episodes of right breast swelling and abscess for 8 years. These were proven to be chronic granulomatous mastitis by tissue biopsies on 3 different occasions. Her condition improved on simi...

BACKGROUND Staphylococcus aureus causes subclinical mastitis as well as persistent and chronic infections in cattle. Bovine mastitis induced by S. aureus is often refractory to antibiotic treatment. Local innate immune defenses play an important role in eliminating the invading bacteria. TLR2 and NOD2 are important pathogen recognition receptors, but their functions have not been investigated i...

Ductal carcinoma in situ (DCIS) is a breast (BC) consisting of malignant cells the ductal lumen without invasion beyond epithelial membrane. The article presents rare clinical case combined course chronic mastitis and 47-year-old female patient who was diagnosed with during instrumental examination, only after trepan biopsy subsequent histological intraductal cancer verified. This may indicate ...

Granulomatous mastitis is a rare, benign , chronic inflammatory condition of the breast. Clinical and radiogical features may mimic breast carcinoma. It represents a therapeutic dilemma and treatment alternatives are still unclear. Generally high recurrence rates are reported after excision. Granulomatous mastitis is a disease of unknow etiology; the most favorable factor is autoimmune reaction...

Although numerous reports on bacteriophages for staphylococci of human origin have appeared, none could be found regarding phages active against staphylococci from bovine sources. This laboratory has been concerned with various phases of bovine mastitis, hence it was of interest to investigate the occurrence and role of bacteriophage in staphylococcal mastitis. While this type of mastitis is pr...

BACKGROUND Idiopathic granulomatous mastitis is a chronic inflammatory disease of the breast, which is often difficult to differentiate both clinically and radiologically from infectious aetiologies such as tuberculosis, fungal infections, and also from malignancy, thus posing a diagnostic dilemma. We present a pictorial review of the commonly encountered imaging findings in idiopathic granulom...

The global dairy industry, the predominant pathogens causing mastitis, our understanding of mastitis pathogens and the host response to intramammary infection are changing rapidly. This paper aims to discuss changes in each of these aspects. Globalisation, energy demands, human population growth and climate change all affect the dairy industry. In many western countries, control programs for co...