objective: in the present study, we examined the effects of memantine administration within the nucleus accumbens on the alterations in brain and adrenal volumes and weight ratios induced by stress from electric foot shock. methods: a group of mice received various doses of memantine (0.1, 0.5 and 1 mg/kg) prior to induction of stress. another group underwent intra-accumbal cannulation after an...

objective(s): due to the prevalence and pervasiveness of stress in modern life and exposure to both chronic and acute stresses, it is not clear whether prior exposure to chronic stress can influence the impairing effects of acute stress on memory retrieval. this issue was tested in this study. materials and methods: adult male wistar rats were randomly assigned to the following groups: control,...

Acute and chronic stress-related mechanisms play an important role in the development of addiction and its chronic, relapsing nature. Multisystem adaptations in brain, body, behavioral, and social function may contribute to a dysregulated physiological state that is maintained beyond the homeostatic range. In addition, chronic abuse of substances leads to an altered set point across multiple sy...

The present study aimed at investigating the effects of chronic multiple stress on learning and memory functions of rats. Adult male Wistar rats were randomly divided into stressed and control groups. Rats in the stressed group were irregularly and alternately exposed to the situation of vertical revolution, sleep deprivation, noise stimulation, and night illumination 6 h per day for 6 weeks to...

the recent literatures indicate that central nervous system (cns) is highly vulnerable to systemic hyperthermia induced by whole body heating on conscious animals. in the present study, cerebral electrical activity or eeg (electroencephalogram) following exposure to high environmental heat has been studied in moving rats. rats were divided into three group (i) acute heat stress-subjected to a s...

objective: the main purpose of this study was to investigate the effectiveness of lazarus multimodal psychotherapy (mmt) on perceived stress in individuals with multiple sclerosis (ms). methods: through a quasi-experimental design, forty patients in qazvin city in iran were selected by convenient sampling and then divided into two groups: experimental and control groups. after group assignment,...

conclusions this study showed that mbsr training can reduce mean depression, anxiety and stress scores in patients with ms. these findings suggest that mbsr is useful for psychological problems such as depression, anxiety and stress in patients with ms. patients and methods this randomized controlled clinical trial was performed in 2013 in ahvaz ms society. forty eight patients were selected by...