BACKGROUND Contrast-induced nephropathy (CIN) in native kidneys is associated with a significant increase in mortality and morbidity. Data regarding CIN in renal allografts are limited, however. We retrospectively studied CIN in renal allografts at our institution: its incidence, risk factors, and effect on long-term outcomes including allograft loss and death. METHODS One hundred thirty-five...

Objective: In this study, we investigated the correlation between the degree and timing of chemotherapyinduced neutropenia (CIN) caused by the DCF (docetaxel-platinum-fluorouracil) regimen as first-line chemotherapy and the survival of patients with advanced gastric cancer. Methods: We retrospectively analysed 110 patients diagnosed with advanced gastric cancer between 2007 and 2012 at our hosp...

Background: Contrast-induced nephropathy (CIN) is a major side effect of intravenous iodinated contrast and causes both short- and long-term adverse effects. While diagnostic and interventional procedures of brain ischemia are recently advanced, it is necessary to be cautious about its major side effect. Objectives: To evaluate CIN and its risk factors in neurology patients after brain and cer...

Background: Cervical carcinoma is the most common cancer with a prevalence of 28.6% all cancers in women Indonesia and one leading causes death among gynecologic malignancies. Prevention understanding are needed terms initiation development precancerous lesions into cervical cancer. About 90% squamous cell carcinomas that develop from intraepithelial neoplasia. Epidermal Growth Factor Receptor ...

Cancer is one of the leading causes of death, and despite increased research in recent years, control of advanced-stage disease and optimal therapeutic responses remain elusive. Recent technological improvements have increased our understanding of human cancer as a heterogeneous disease. For instance, four hallmarks of cancer have recently been included, which in addition to being involved in c...

OBJECTIVES Reduced number and impaired function of circulating endothelial progenitor cells (EPCs) in patients with chronic kidney disease have been reported. However, there is little data about the association between circulating EPC levels and risk of contrast-induced nephropathy (CIN). The aim of this study was to investigate the relationship between circulating EPCs and CIN in patients afte...

Cancer cells exhibit high levels of chromosome instability (CIN), and considerable interest surrounds the possibility that inactivation of the spindle checkpoint is involved. However, homozygous disruption of Mad and Bub checkpoint genes in metazoans causes cell death rather than CIN. We now report the isolation and characterization of blastocysts and two independent mouse embryonic fibroblast ...

Background: In Bangladesh, loop electrosurgical excision procedure (LEEP) is an ongoing program of government health service for the management cervical intra-epithelial neoplasia (CIN) 2 and 3. The aim this study was to evaluate outcome following treatment Methods: This descriptive cross-sectional conducted in outpatient department (OPD), gynaecology obstetrics department, Rangpur Medical Coll...

Abstract Chromosomal instability (CIN) is a hallmark of cancer and contributes to tumorigenesis tumor progression. While structural CIN (S-CIN) leads chromosome aberrations, whole (W-CIN) defined by perpetual gains or losses chromosomes during mitosis causing aneuploidy. Mitotic defects, but also abnormal DNA replication (replication stress) can lead W-CIN. However, the functional link between ...