Mitral regurgitation due to 'floppy' valves is frequently associated with areas of medical necrosis in the ascending aorta. Application of the aortic clamp to such an area during valve replacement may produce an intimal tear followed by acute dissection. This complication occurred in three patients and was treated successfully by repair of the tear in the two cases where the dissection was obse...

When assessing the function of the mitral valve at operation by palpation or inspection, the surest way to prevent systemic (cerebral) embolism is to have the ascending aorta occluded by a clamp. A technique is described which allows safe assessment of mitral valve function by aortic root and left ventricular perfusion, giving a beating-heart preparation with the aorta cross-clamped. This metho...

Methods 59 patients undergoing elective CABG were prospectively evaluated. Two groups of patients were formed, based upon the aortic clamping strategy utilized to achieve myocardial revascularization. The single aortic clamp group (SC) whom CABG was performed using a single period of aortic clamping, whereas 22 patients in the multiple aortic clamp group (MC) group had their aorta side-clamped ...

A 71-year-old woman with isthmic aortic coarctation underwent aortic valve replacement and coronary bypass. Before aortic clamping, end-to-side anastomosis to descending aorta was performed. After cardiac surgery, the graft was directed posterior to the inferior vena cava and anastomosed to the ascending aorta by using a side-biting clamp (Fig. 1). Fig. 1. Three-dimensional computed tomographic...

A 62-year-old man was referred for an aortic-valve surgery because of severe aortic stenosis. Thirty years ago, he had undergone a mitral valve commissurotomy and after 9 years, the valve had been replaced by a mechanical valve. He had been undergoing hemodialysis for the past 8 years. A computed tomographic (CT) scan of the chest and abdomen showed a dense circumferential calcification in the ...

Background and Purpose K V 1.3 channels are expressed in vascular smooth muscle cells (VSMCs), where they contribute to proliferation rather than contraction participate remodelling. also macrophages, assemble with 1.5 (K 1.3/K 1.5), whose activation generates a current. In the ratio is increased by classical (M1). Whether these involved angiotensin II (AngII)‐induced remodelling, whether can m...

Aortic ischemia-reperfusion (AIR) induced lung injury has already been documented. Kupffer cell blockage (KCB) with gadolinium chloride (GdCl3) has also been shown to attenuate remote organ damage caused by ischemia reperfusion. The present study was designed to examine the effect of GdCl3 in lung ischemia-reperfusion injury induced by aortic occlusion. Thirty-two rats were randomly allocated t...