نتایج جستجو برای: clasical cytogenetics

تعداد نتایج: 10228  

Journal: :Journal of Medical Genetics 1989

Journal: :HortScience 2006

Journal: :Applied Mathematics and Computation 2021

We present a generalized study and characterization of the integrability properties derivative non-linear Schrödinger equation in 1+1 dimensions. A Lax pair is derived for this by means Miura transformation singular manifold method. This procedure, together with Darboux transformations, allow us to construct wide class rational soliton-like solutions. Clasical Lie symmetries have also been comp...

2011
Wei Wu Xiaoli Yang Charles C. Tseng

Learning human cytogenetics is important for biology education and training of clinical cytogenetics technologists. To increase the resources of metaphase spreads with different chromosomes shapes for student practice, we describe effective algorithms for such purposes to enhance our cytogenetics tutorial program.

Journal: :Blood 2016
Hervé Avet-Loiseau Rafael Fonseca David Siegel Meletios A Dimopoulos Ivan Špička Tamás Masszi Roman Hájek Laura Rosiñol Vesselina Goranova-Marinova Georgi Mihaylov Vladimír Maisnar Maria-Victoria Mateos Michael Wang Ruben Niesvizky Albert Oriol Andrzej Jakubowiak Jiri Minarik Antonio Palumbo William Bensinger Vishal Kukreti Dina Ben-Yehuda A Keith Stewart Mihaela Obreja Philippe Moreau

The presence of certain high-risk cytogenetic abnormalities, such as translocations (4;14) and (14;16) and deletion (17p), are known to have a negative impact on survival in multiple myeloma (MM). The phase 3 study ASPIRE (N = 792) demonstrated that progression-free survival (PFS) was significantly improved with carfilzomib, lenalidomide, and dexamethasone (KRd), compared with lenalidomide and ...

2018
Naery Yang Yeung Chul Mun Chu-Myong Seong Hee Jin Huh Jungwon Huh

In multiple myeloma (MM), hyperdiploidy (HD) is known to impart longer overall survival. However, it is unclear whether coexistent HD ameliorates the adverse effects of known high-risk cytogenetics in MM patients. To address this issue, we investigated the clinicopathological characteristics of HD with high-risk cytogenetics in MM. Ninety-seven patients with MM were included in the study. For m...

Journal: :Procesamiento del Lenguaje Natural 2013
Patricio Martínez-Barco Antonio Ferrández Rodríguez David Tomás Elena Lloret Estela Saquete Boró Fernando Llopis Jesús Peral Cortés Manuel Palomar José Manuel Gómez Soriano María Teresa Romá-Ferri

The main objective of this project is based on the need to reconsider the clasical HLT philosophy to adapt it, not only to the currently available resources (unstructured data with multimodality, multilinguality and different levels of formality) but also to the real needs of the final users. In order to reach this objective it is necessary to include the understanding as well as the generation...

2011
Farouq F. Said Basem F. Ali Darrin Richeson

In the title compound, C(19)H(36)N(3) (+)·I(-), the orientation of the cyclo-hexyl rings around the planar (sum of N-C-N angles = 360°) CN(3) (+) unit produces steric hindrance around the N-H groups. As a consequence of this particular orientation of the tricyclo-hexyl-guanidinium cation (hereafter denoted CHGH(+)), hydrogen bonding is restricted to classical N-H⋯I and non-clasical (cyclo-hex-y...

Journal: :Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2014
Sunila Tashfeen Suhaib Ahmed Farhat Abbas Bhatti Nadir Ali

OBJECTIVE To compare the sensitivity and specificity of Real Time Polymerase Chain Reaction (RT-PCR) with conventional cytogenetics in diagnosis of chronic myeloid leukemia. STUDY DESIGN A cross-sectional, analytical study. PLACE AND DURATION OF STUDY The Armed Forces Institute of Pathology (AFIP), Rawalpindi, from December 2010 to January 2012. METHODOLOGY A total number of 40 patients w...

2016
Caroline E. Sloan Marlise R. Luskin Anne M. Boccuti Alison R. Sehgal Jianhua Zhao Robert D. Daber Jennifer J. D. Morrissette Selina M. Luger Adam Bagg Phyllis A. Gimotty Martin Carroll

BACKGROUND Although cytogenetics-based prognostication systems are well described in acute myeloid leukemia (AML), overall survival (OS) remains highly variable within risk groups. An integrated genetic prognostic (IGP) model using cytogenetics plus mutations in nine genes was recently proposed for patients ≤60 years to improve classification. This model has not been validated in clinical pract...

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