Orofacial clefts are one of the commonest birth defects, and may be associated with other congenital anomalies. The majority of these orofacial clefts are nonsyndromic . A significant percentage of these clefts both syndromic and non-syndromic may have associated anomalies. Apart from reviewing other studies, this article also analyses a study of associated anomalies from a tertiary cleft centr...

introduction: a cleft lip with or without a cleft palate is one of the major congenital anomalies observed in newborns. this study explored the risk factors for oral clefts in gorgan, northern iran.  materials and methods: this hospital-based case-control study was performed in three hospitals in gorgan, northern iran between april 2006 and december 2009. the case group contained 33 newborns wi...

Since 2005 in France, the national technical committee of prenatal ultra-sound screening (CNTE) has recommended that pregnant women have a routine second trimester ultrasound screening for facial clefts. The view on the coronal reference plane visualizes the continuity of the upper lip, and makes it possible to detect most facial clefts, but not isolated palatal clefts.

M yocardial clefts are a recently described finding and are increasingly noted with the growing use of cardiac MRI. We describe a patient with multiple myocardial clefts on MRI. Case A 45-year-old man came for cardiac screening evaluation because of an abnormal ECG. He had undergone occupational health screening 8 years previously and had been noted to have T-wave inversion from V2 to V4. He ha...

Oral clefts are common birth defects that have a major impact on the affected individual, their family and society. World-wide, the incidence of oral clefts is 1/700 live births, making them the most common craniofacial birth defects. The successful prediction of oral clefts may help identify sub-population at high risk, and promote new diagnostic and therapeutic strategies. Nevertheless, devel...

BACKGROUND Oral clefts are one of the most common birth defects worldwide. They require multiple healthcare interventions and add significant burden on the health and quality of life of affected individuals. However, not much is known about the long term effects of oral clefts on health and healthcare use of affected individuals. In this study, we evaluate the effects of oral clefts on hospital...

OBJECTIVE To evaluate potential abnormalities in brain structure of children and adolescents with unilateral clefts. DESIGN Case-control study. SETTING Tertiary care center. PARTICIPANTS Boys aged 7 to 17 years with right (n=14) and left (n=19) clefts were compared with healthy age-matched boys (n=57). MAIN EXPOSURES Structural brain measures were obtained using magnetic resonance imagi...

Introduction: A cleft lip with or without a cleft palate is one of the major congenital anomalies observed in newborns. This study explored the risk factors for oral clefts in Gorgan, Northern Iran.  Materials and Methods: This hospital-based case-control study was performed in three hospitals in Gorgan, Northern Iran between April 2006 and December 2009. The case group contained 33 newborns...

Orofacial clefts are one of the most common congenital anomalies. The incidence is approximately 1 : 500 to 1 : 550 births [1]. The group of orofacial anomalies is heterogeneous. It comprises “typical” orofacial clefts ((cleft lip (CL), cleft lip and cleft palate (CLP) and cleft palate only (CP)) and “atypical” clefts (median, transversal, oblique and other Tessier’s types of facial clefts)[1]....