Toxicology is the study of poisons and poisoning and has an ancient and venerable history. Although there have been numerous notorious poisonings throughout the ages and rather astute descriptions of toxic agents, the scientific study of toxicology did not commence until the 19th century. There was rapid development of analytical methods in the late 19th century and then an acceleration of both...

Conjugation is an important mechanism for the rapid inactivation and extensive removal of drugs and poisons from the body, and as such it is of major significance in clinical toxicology. The capacity for conjugation of some drugs is large, but with others, saturation may occur with overdosage or even high therapeutic doses. Glutathione conjugation is an important mechanism of protection against...

In the editorial by Dr. Reza Afshari “Empowerment of Medical Toxicology in Asia Pacific Region” published in the Asia Pacific Journal of Medical Toxicology (APJMT) (1), the role of Asia Pacific Association of Medical Toxicology (APAMT) in promoting medical toxicology has been discussed and some suggestions have been made regarding how to promote this field of medical sciences in the region. The...

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toxicology, as a multidisciplinary field, provides career opportunities for graduates with medical, or veterinarian, pharmacological, pharmaceutical, biological, microbiological, molecular biological, chemical, biochemical, and genetic backgrounds. today, however, specialists with a university degree in toxicology or a postgraduate training in toxicology have a clear advantage. postgraduate dip...

In the last issue of the Asia Pacific Journal of Medical Toxicology, Dr. Reza Afshari raised the question of what are the best scientific areas of focus of toxicology for “low income countries and how such research might be achieved (1). South-south collaboration, in which developing countries share resources, was one of the proposed solutions. Rather than limit discussion to “low income” coun...

In order to address the field of tension between toxicology as well as basic and clinical sciences, we closely cooperate with our partner journal Archives of Toxicology. To give our readers a rapid overview of recent developments we have summarized the key messages of the most cited publications. For better orientation we grouped the articles into the categories inorganic compounds (Table 1), t...

*Reproductive Toxicology Group, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709; ^Department of Toxicology, Crop Protection Division, Ciba-Geigy, Greensboro, North Carolina; ^Comparative Medicine Clinical Research Center, Departments of Comparative Medicine and Obstetrics & Gynecology, The Bowman Gray School of Medic...