Neurodegenerative diseases have traditionally been defined as clinico-pathological entities. The clinician observes characteristic clusters of symptoms that relate to the anatomical distribution of the lesion. Typically, these symptoms progress in a characteristic sequence allowing the clinician to make a provisional diagnosis. At autopsy, the pathologist examines the nature and distribution of...

Background Post-hepatectomy liver failure (PHLF) is a fatal complication after resection in patients with hepatocellular carcinoma (HCC). It of clinical importance to estimate the risk PHLF preoperatively. Aims This study aimed develop and validate prediction model based on preoperative gadoxetic acid–enhanced magnetic resonance imaging HCC. Methods A total 276 were retrospectively included ran...

Nodal staging in breast cancer is a key predictor of prognosis. This paper presents the results of potential clinicopathological predictors of axillary lymph node involvement and develops an efficient prediction model to assist in predicting axillary lymph node metastases. Seventy patients with primary early breast cancer who underwent axillary dissection were evaluated. Univariate and multivar...

PURPOSE To investigate the association between C-reactive protein/albumin ratio (CAR), an inflammation-based prognostic score, and clinicopathological factors, as well as its association with long-term outcomes in patients with operable non-small cell lung cancer (NSCLC). METHODS A total of 617 operable NSCLC patients were retrospectively evaluated and the data of preoperative serum CRP and s...

Background: Cancer stem cells (CSCs) are a group of tumor cells with self-renewal property and differentiation potential. CSCs play a crucial role in malignant progression of several types of tumors. However, what is still controversial is the clinicopathological relationship between Nanog marker and its prognostic value in the patients with breast cancer. The expression of Nanog in the patient...

Objective: We aimed to evaluate the prognostic role of preoperative serum cancer antigen 125 (CA-125) in endometrioid endometrial for determining cut-off values clinicopathological factors.
 Study design: 161 patients were included study. The inclusion criteria histopathological confirmation and with CA-125 levels measured at most ten days before surgery. association between value variable...

Gastric pseudomelanosis is exceedingly rare. To the best of our knowledge, there have been only six reported cases in the literature of gastric pseudomelanosis. We report a case of an 86 year-old woman with marked iron deficiency anemia who was found to have characteristic speckled pattern of grey-black pigmentation on endoscopic examination. Histologically, the gastric biopsy revealed characte...

The great majority of malignant peripheral nerve sheath tumors (MPNSTs) exhibit Schwann differentiation. Few MPNSTs with perineurial differentiation are also named malignant perineuriomas. Benign perineurioms were classified as intraneural, extraneural (soft tissue), sclerosing, and reticular variant. Histopathological features of intraneural perineurioma are individual nerve axons surrounded b...