The clinical and basic science research domains present exciting and difficult data integration issues. Solving these problems is crucial as current research efforts in the field of biomedicine heavily depend upon integrated storage, querying, analysis, and visualization of clinicopathology information, genomic annotation, and large scale functional genomic research data sets. Such large scale ...

BACKGROUND Gastric cancer is a heterogeneous disease with respect to its molecular and histopathological features. Proximal gastric carcinoma (PGC) and distal gastric carcinoma (DGC) are two distinct clinical entities, suggesting the existence of different pathogenic mechanisms. PGC arises in a narrow region of the proximal stomach below the gastroesophageal junction. It accounts for around hal...

Prompt and accurate assessment of the origins of azotemia—pre­ renal, renal, and/or postrenal—is essential to the proper management of azotemic patients. Prerenal azotemia occurs when decreased renal perfusion results in a diminished glomerular filtra­ tion rate (GFR); common causes of pre­ renal azotemia include volume depletion, vascular collapse, thrombotic diseases, and shock (cardiogenic, ...