نتایج جستجو برای: clustered corm percent

تعداد نتایج: 127265  

2015
Shulong Zhang Shuyun Zheng Xin Wang Qiankun Shi Xiang Wang Shoutao Yuan Guozheng Wang Zhenling Ji Frédéric André

OBJECTIVE Damage to intestinal epithelial tight junctions plays an important role in sepsis. Recently we found that Carbon Monoxide-Releasing Molecule-2 (CORM-2) is able to protect LPS-induced intestinal epithelial tight junction damage and in this study we will investigate if CORM-2 could protect intestinal epithelial tight junctions in the rat cecal ligation and puncture (CLP) model. MATERI...

Journal: :Journal of Experimental Botany 2009
Maria Lundmark Vaughan Hurry Line Lapointe

In Crocus vernus, a spring bulbous species, prolonged growth at low temperatures results in the development of larger perennial organs and delayed foliar senescence. Because corm growth is known to stop before the first visual sign of leaf senescence, it is clear that factors other than leaf duration alone determine final corm size. The aim of this study was to determine whether reduced growth ...

2010
Yunwei Wei Ping Chen Marco de Bruyn Weihui Zhang Edwin Bremer Wijnand Helfrich

BACKGROUND Hepatic ischemia-reperfusion injury (I/Ri) is a serious complication occurring during liver surgery that may lead to liver failure. Hepatic I/Ri induces formation of reactive oxygen species, hepatocyte apoptosis, and release of pro-inflammatory cytokines, which together causes liver damage and organ dysfunction. A potential strategy to alleviate hepatic I/Ri is to exploit the potent ...

Journal: :فصلنامه علمی اکوفیزیولوژی گیاهان زراعی 0

the saffron understanding the factors that increased the quality and quantity of product in order to achieve optimum performance it is important, in this regard, the use of fertilizers and different densities corm are the most important factor. in this regard, an experiment in 1394 to factorial design in a randomized complete block design with three replications in the village davoodabad locate...

Journal: :Hypertension 2012
Yilin Ren Martin A D'Ambrosio Hong Wang John R Falck Edward L Peterson Jeffrey L Garvin Oscar A Carretero

Carbon monoxide (CO) is a physiological messenger with diverse functions in the kidney, including controlling afferent arteriole tone both directly and via tubuloglomerular feedback (TGF). We have reported that CO attenuates TGF, but the mechanisms underlying this effect remain unknown. We hypothesized that CO, acting via cGMP, cGMP-dependent protein kinase, and cGMP-stimulated phosphodiesteras...

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009
Mathieu Desmard Kelly S Davidge Odile Bouvet Didier Morin Damien Roux Roberta Foresti Jean D Ricard Erick Denamur Robert K Poole Philippe Montravers Roberto Motterlini Jorge Boczkowski

The search for new molecules to fight Pseudomonas aeruginosa is of paramount importance. Carbon monoxide (CO) is known to act as an effective inhibitor of the respiratory chain in P. aeruginosa, but the practical use of this gas as an antibacterial molecule is hampered by its toxicity and difficulty to manipulate. Here, we show that a water-soluble CO releaser (CORM-3) possesses bactericidal pr...

2015
Peng Wang Jian Huang Yi Li Ruiming Chang Haidong Wu Jiali Lin Zitong Huang Paul Evans

Carbon monoxide (CO) has shown various physiological effects including anti-inflammatory activity in several diseases, whereas the therapeutic efficacy of CO on sepsis-induced acute kidney injury (AKI) has not been reported as of yet. The purpose of the present study was to explore the effects of exogenous CO on sepsis-induced AKI and nucleotide-binding domain-like receptor protein 3 (NLRP3) in...

2012
Hoda Hassan

Future Internet design demands revolutionary approaches unfettered by legacy constraints and concepts. This paper presents a clean-slate Concern-Oriented Reference Model (CORM) for architecting future computer networks based on novel network design principles. CORM realizes the network as a software-dependent complex system. It defines the network design space in terms of function, structure an...

Journal: :Molecular pharmacology 2010
Christian I Schwer Manuel Mutschler Patrick Stoll Ulrich Goebel Matjaz Humar Alexander Hoetzel Rene Schmidt

Proliferation of pancreatic stellate cells (PSCs) plays a cardinal role during fibrosis development. Therefore, the suppression of PSC growth represents a therapeutic option for the treatment of pancreatic fibrosis. It has been shown that up-regulation of the enzyme heme oxygenase-1 (HO-1) could exert antiproliferative effects on PSCs, but no information is available on the possible role of car...

Journal: :The Journal of pharmacology and experimental therapeutics 2006
Philip Sawle Jehad Hammad Ian J S Fairlamb Benjamin Moulton Ciara T O'Brien Jason M Lynam Anne K Duhme-Klair Roberta Foresti Roberto Motterlini

Carbon monoxide-releasing molecules (CO-RMs) are compounds capable of delivering controlled amounts of CO within a cellular environment. Ruthenium-based carbonyls [tricarbonyldichloro ruthenium(II) dimer and tricarbonylchloro-(glycinato)ruthenium(II)] and boronacorbonates (sodium boranocarbonate) have been shown to promote vasodilatory, cardioprotective, and anti-inflammatory activities in a va...

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