Background: Human Cytomegalovirus (CMV) is one of the most significant pathogens infecting immunosuppressed individuals. CMV is known to be a significant cause of morbidity and mortality following blood transfusion in immunocompromised individuals. The immunosuppressed population for whom CMV free blood products are requested is increasing due to advances in medical care. The most effective way...

with Anti-MAG/SGPG Antibody–Associated Neuropathy Sachiko Irie, MD, PhD,* Naomi Kanazawa, BS,† Mieko Ogino, MD, PhD,* Toyokazu Saito, MD, PhD,* and Tadao Funato, PhD‡ In a recent study by Yuki and colleagues, cytomegalovirus (CMV) DNA was detected in sera from 23 of 26 patients (88%) with IgM anti-myelin–associated glycoprotein (antiMAG)/sulfated glucuronyl paragloboside (SGPG) antibody– associ...

BACKGROUND Samples from babies exhibiting clinical symptoms suggestive of congenital infection are referred regularly to NICD, New Delhi,, from Government Hospitals located in Delhi and a home for abandoned children (Palna), for the diagnosis of etiological agents like toxoplasma, rubella, CMV and herpes. Blood samples of mothers of most of the affected babies are also received. OBJECTIVE Eva...

background: cytomegalovirus (cmv) infection is associated with significant maternal and fetal consequences. the aim of pre­sent study was to determine the current prenatal cmv seroprevalence in eastern azerbaijan and evaluate the routine labora­tory diagnostic techniques of anti-cmv immunoglobulin m (igm) and immunoglobulin g (igg). methods: during the present prospective cross-sectional study,...

background beta-thalassemia patients receive blood products from blood transfusion centers repeatedly. blood transfusion can transmit cytomegalovirus (cmv) and toxoplasma gondii. the aim of this study was serological evaluation of these two infectious agents in thalassemia patients. materials and methods in a cross-sectional study, the enzymelinked immunosorbent assay (elisa) testing was perfor...

CMV diseases predominantly occur as an opportunistic infection in patients with severe immunosuppression, such as cancer and renal failure patients, and rarely occur in immunocompetent patients. This study aimed to investigate the prevalence of CMV infection in patients undergoing hemodialysis and to compare the results of different serological tests for CMV infection. Data were collected from ...

BACKGROUND & OBJECTIVES We undertook this study to determine the infectious aetiology of congenital cataract based on the presence of IgM antibodies to TORCHES [(Toxoplasma gondii (T. gondii), Rubella virus (RV), Cytomegalovirus (CMV), Herpes simplex virus (HSV) and Syphilis (caused by Treponema pallidum)] in the serum samples of congenital cataract patients. METHODS Serum samples collected f...

BACKGROUND Up to 90% of neonates with congenital or perinatal cytomegalovirus (CMV) infection are asymptomatic, and little is known about CMV-associated thrombocytopenia after the neonatal period. We investigated the clinical findings of a series of infants diagnosed with CMV infection and thrombocytopenia. METHODS From July 2005 to July 2008, infants aged younger than 6 months with thrombocy...

   Background and aims: Maternal primary and recurrent infection of cytomegalovirus (CMV) may be transmitted to the fetus during pregnancy and may have complications such as death or growth, along with the development retardation of the fetus and infant. The aim of this study was to determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies against CMV in you...