نتایج جستجو برای: cns depressant

تعداد نتایج: 106579  

Journal: :International Journal of Current Science Research and Review 2021

Young edible bamboo shoot (Muia in Kokborok-the third Official Language of Tripura, India) Melocanna baccifera is widely used as a raw food ingredient different dishes Tribal Tripura. Methanolic extract (MEMB) revealed the presence bioactive constituents like alkaloids, fixed oil, flavonoids, triterpinoids, glycosides carbohydrate, protein, and minerals sodium, potassium, calcium, chloride, pho...

Journal: :Turkish journal of medical sciences 2014
Muhammad Riaz Muhammad Zia-Ul-Haq Najm Ur-Rahman Mansoor Ahmadi

AIM To investigate methanol extracts of various parts of Rubus fruticosus L. (Rosaceae) for various neuropharmacological activities, such as anxiolytic, muscle relaxant, antidepressant, and sedative activities. MATERIALS AND METHODS The extracts were administered to albino mice orally at doses of 100, 300, and 500 mg/kg. The antidepressant activity was determined by using the forced swimming ...

Al Mamun Badrul Alam, Efte Kharul Alam Hajera Khatun Rajib Majumder Safkath Ibne Jami

Objective: Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. Materials and methods: Neuropharmacology study was done by open field and hole cro...

Journal: :Chemical & pharmaceutical bulletin 2001
T Kimura S Yao K Watanabe S Kondo I K Ho I Yamamoto

Methyl (2), ethyl (3), propyl (4), butyl (5), allyl (6), benzyl (7), o-, m-, p-xylyl (8-10), and alpha-phenylethyl (11) derivatives of arabinofuranosyluracil (1) were synthesized and their pharmacological effects in mice were examined by using hypnotic activity and synergism with pentobarbital as indices for the CNS depressant effects. At a dose of 2.0 micromol/mouse by intracerebroventricular ...

2011
FO Silva MGV Silva GS Cerqueira EB Sabino AAC Almeida JP Costa RM Freitas

The central nervous system (CNS) depressant and anticonvulsant activities of iso-6-spectaline (SPEC) were investigated in animal models. The SPEC from Senna spectabilis var. excelsa (Schrad) (0.1, 0.5 and 1.0 mg/ kg) injected by oral route (p.o.) in mice caused a significant decrease in the motor activity up to 30 days after the administration and in the dose of 1.0 mg/kg significantly reduced ...

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