The incidence of nosocomial infections with methicillin-resistant Staphylococcus aureus is of great concern in Japan and the developed world as a whole. Simple typing techniques like coagulase and phage typing are quick and useful for monitoring and evaluating these organisms. In view of this, the current status of antimicrobial susceptibility in Staphylococcus aureus (S. aureus) isolates in Ok...

PURPOSE To determine whether a 3-day application of ofloxacin results in the selection of fluoroquinolone-resistant conjunctival coagulase-negative Staphylococcus. DESIGN Prospective randomized trial. METHODS Patients scheduled for ocular surgery were randomized to a control (89 eyes) or study group (70 eyes). The study group received topical ofloxacin (0.3%) four times a day for 3 days. Co...

Numerous investigations have attempted to define those factors responsible for the virulence of Staphylococcus aureus.'" Almost all of the enzymes and exotoxins produced by staphylococci have at some time been purported to be responsible for their pathogenicity but none has been clearly demonstrated of paramount importance.'" The relation of coagulase and alpha hemolysin to the pathogenesis of ...

The role of coagulase in staplhylococcal infections is tincertain. It has been clemonstrated(1) that coagulase-negative hemolytic staphylococci wllen treated witlh coagulase and injected intracerebrally into mice exlhibit a higlher degree of virulence than the same organisms without treatment with coagulase. Other workers(2,3) have also found an association of coagtulase with virulence. However...

Staphylococcus chromogenes is one of the main coagulase-negative staphylococci isolated from mastitis of dairy cows. We describe S. chromogenes isolates that can clot plasma. Since the main pathogen causing mastitis is coagulase-positive Staphylococcus aureus, the coagulase-positive phenotype of S. chromogenes described here can easily lead to misidentification.

Aerobic In clusters ● Coagulase (+): Staphylococcus. aureus ● Coagulase (-):Staphylococcus lugdunensis or other coagulase-negative Staphylococcus In pairs/chains ● Optochin sensitive: Streptococcus pneumoniae ● Alpha-hemolytic: Viridans group Streptococcus, Enterococcus species ● Beta-hemolytic: ○ Group A Strep (Streptococcus pyogenes) ○ Group B Strep (Streptococcus agalactiae) ○ Group C, D, G ...

One thousand and thirty-five clinical isolates of the genus staphylococcus were used to compare the coagulase test with the deoxyribonuclease (DNase) and heat-stable nuclease tests as methods for identifying Staphylococcus aureus. Conflicting results were obtained with 65 isolates when the coagulase test was compared with the DNase test but with only one isolate when the coagulase test was comp...

One thousand and thirty-five clinical isolates of the genus staphylococcus were used to compare the coagulase test with the deoxyribonuclease (DNase) and heat-stable nuclease tests as methods for identifying Staphylococcus aureus. Conflicting results were obtained with 65 isolates when the coagulase test was compared with the DNase test but with only one isolate when the coagulase test was comp...