Background: The liver is the cornerstone of the coagulation system. The physiology of blood coagulation is closely linked to liver function as the liver synthesizes most of the factors of the coagulation cascade and fibrinolytic proteins. Objective: The objective of this study was to evaluate coagulation abnormalities associated with chronic liver diseases and determine the coagulation abnormal...

Background: Postpartum hemorrhage (PPH) is a leading cause of severe maternal morbidity and mortality worldwide which leads to massive blood loss. Coagulation abnormalities in response trauma or infection are latent that might aggravate PPH.

Coagulation studies were performed on nine children with burns. Four of these children received treatment which included intravenous dextran; all four showed abnormalities of coagulation and two of them developed a bleeding state. No abnormalities of haemostasis were detected in the remaining five children who had comparable degrees of burns but whose treatment did not include intravenous dextran.

Bleeding following cardiac surgery is a serious event with potentially life-threatening consequences. Preoperative recognition of coagulation abnormalities and detection of cardiopulmonary bypass (CPB) related coagulopathy could aid in the start of preventive treatment strategies that minimize perioperative blood loss. Most algorithms that analyze thromboelastometry coagulation tests in electiv...

OBJECTIVE To investigate liver function and coagulation disorders in patients with a Fontan circulation at different time intervals after surgery. DESIGN Retrospective analysis of clinical data and cross sectional study relating liver function and coagulation profile to time since surgery, in 28 surviving patients after the modified Fontan procedure. PATIENTS 20 patients (71%) with atriopul...