Background and Objective: Extracellular RNA (exRNA) is an evolving concept. In one hand, more endogenous types are detected in various biofluids or found local extracellular space. These exRNAs include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular (circRNAs), piwi-interacting (piRNAs), transfer (tRNAs) protein-coding messenger (mRNAs). ExRNA profilings associated with many physio...