BACKGROUND & AIMS There is no agreement as to whether F-18 fluorodeoxyglucose positron emission tomography and computed tomography (FDG PET/CT) screening for advanced colorectal neoplasms is meaningful. This retrospective study was undertaken to determine whether FDG PET/CT may be a valuable screening tool for the detection of advanced colorectal neoplasms. METHODS A retrospective review of t...

Conventional colonoscopy is regarded as the gold standard procedure for the diagnosis of colorectal neoplasms despite its several limitations including invasiveness, discomfort and potential complications. Colon capsule endoscopy (CCE) could be an attractive alternative method to the invasive colonoscopy for the diagnosis of colorectal cancer and polyps. Publications regarding the use of CCE fo...

This retrospective study aimed to clarify the clinical characteristics of advanced colorectal neoplasms after colonoscopy, likely to have been missed on the previous colonoscopy. We reviewed a total of 5,768 consecutive colonoscopies performed from April 2010 to September 2013 in 4,841 patients, and analyzed advanced colorectal neoplasms after colonoscopy, particularly focusing on their morphol...

BACKGROUND Information on the impact of cecal insertion time on colorectal neoplasm detection is limited. Our objective was to determine the association between cecal insertion time and colorectal neoplasm detection rate in colonoscopy screening. METHODS We performed a cross-sectional study of 12,679 consecutive subjects aged 40-79 years undergoing screening colonoscopy in routine health chec...

PURPOSE Circulating microRNAs (miRNA) are emerging as promising diagnostic biomarkers for colorectal cancer, but their usefulness for detecting early colorectal neoplasms remains unclear. This study aimed to identify serum miRNA biomarkers for the identification of patients with early colorectal neoplasms. EXPERIMENTAL DESIGN A cohort of 237 serum samples from 160 patients with early colorect...

Peroxiredoxins (Prxs) are novel group proteins with efficient antioxidant capacity, and some of them also have effects on cell proliferation, differentiation, apoptosis, and chemotherapy and radiotherapy resistance. Altogether six distinct Prxs expressions were investigated in histological samples of colorectal neoplasm and the distant normal tissues and investigated associatedly with parameter...

OBJECTIVE To determine the prevalence of colorectal neoplasia detected by rescreening people with average risk five years after initial screening by flexible sigmoidoscopy. DESIGN Prospective survey of results of a colorectal cancer screening program. PARTICIPANTS People aged 55-64 years with no symptoms or family history of colorectal cancer who were recruited from the community for flexib...

Objective We investigated whether dual-time-point 18-Fluorodeoxyglucose (18FDG) positron emission tomography/computed tomography (PET/CT) could improve the positive predictive value for detecting advanced colorectal neoplasms (cancer, adenoma ≥10 mm or adenoma with high-grade dysplasia). Methods We retrospectively searched for consecutive patients with a known primary cancer, who had a colonic ...

Benign neoplasms of the colon, rectum, anus and anal canal are true neoplasia colon mucosa associated with a high risk colorectal cancer (CC). The literature review analyzes epidemiology, factors, modern methods diagnosis treatment, describes priority minimally invasive interventions for benign tumors.