نتایج جستجو برای: comparative effectiveness research
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A learning health system is one in which clinical information and research are continually used to improve the processes, outcomes, and quality of care. No matter which definition of comparative effectiveness research (CER) or patient-centered outcomes research (PCOR) is preferred, there is nearly universal agreement that a core feature of these research efforts is the need to engage decision m...
Sixteen months ago, comparative effectiveness research (CER) began its rapid rise, when the American Recovery and Reinvestment Act of 2009 allocated $1.1 billion for CER. This progress report summarizes how the recipients of the funds-the National Institutes of Health, Agency for Healthcare Research and Quality, and Office of the Secretary of the U.S. Department of Health and Human Services-are...
the purpose of this quantitative study was to investigate the relation between efl teachers’ self-efficacy beliefs and their success. moreover, the study was an analysis of the teacher age, gender and years of teaching experience, to examine the manner in which these factors relate to teacher self-efficacy as defined by bandura (1997) and teaching effectiveness as evaluated by their own student...
Biomarker-guided personalized therapies offer great promise to improve drug development and improve patient care, but also pose difficult challenges in designing clinical trials for the development and validation of these therapies. We first give a review of the existing approaches, briefly for clinical trials in new drug development and in more detail for comparative effectiveness trials invol...
Comparative effectiveness research (CER) has assumed an increasing role in drug coverage and, in some cases, pricing decisions in Europe, as decision-makers seek to obtain better value for money. This issue brief comparatively examines the use of CER across six countries--Denmark, England, France, Germany, the Netherlands, and Sweden. With CER gaining traction in the United States, these intern...
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Comparative effectiveness research (CER) can provide valuable information for patients, providers and payers. These stakeholders differ in their incentives to invest in CER. To maximize benefits from public investments in CER, it is important to understand the value of CER from the perspectives of these stakeholders and how that affects their incentives to invest in CER. This article provides a...
The Electronic Data Methods (EDM) Forum announces the launch of eGEMs (Generating Evidence and Methods to improve patient outcomes), a new, free, open access, peer-reviewed e-publication. eGEMs aims to disseminate innovative ideas about how electronic clinical data (ECD) can be leveraged in comparative effectiveness research (CER), patient-centered outcomes research (PCOR) and quality improveme...
The advantages of modeling the unreliability of outcomes when evaluating the comparative effectiveness of health interventions is illustrated. Adding an action-research intervention component to a regular summer job program for youth was expected to help in preventing risk behaviors. A series of simple two-group alternative structural equation models are compared to test the effect of the inter...
BACKGROUND While randomized controlled trials represent the highest level of evidence we can generate in comparative effectiveness research, there are clinical scenarios where this type of study design is not feasible. The Comparative Effectiveness Analyses of Surgery and Radiation in localized prostate cancer (CEASAR) study is an observational study designed to compare the effectiveness and ha...
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