Performance of commercially available component resolved microarray has not been widely evaluated in food allergy. Nut allergy is a prevalent and increasing food allergy in which component resolved diagnosis is crucial. In the context of a multicentric study on pollen and vegetable food allergy in Spain, we enrolled patients (n=100) who had suffered at least two episodes of immediate symptoms a...

BACKGROUND The in vitro diagnosis of pollen-related food allergy presents low specificity and reproducibility with many conventional extracts. This can be improved using natural purified allergens, recombinant purified allergens, or both. OBJECTIVE We compared specific immunoglobulin (Ig) E determination (slgE), the basophil activation test (BAT), the histamine release test (HRT), and the cel...

Performance of commercially available component resolved microarray has not been widely evaluated in food allergy. Fruit allergy is a prevalent food allergy in which component resolved diagnosis is crucial. In the context of a multicentric study on pollen and vegetable food allergy in Spain, we enrolled patients (n=137) who had suffered at least two episodes of immediate symptoms after ingestio...

BACKGROUND Hymenoptera venom-allergic patients frequently present multiple sensitisations. OBJECTIVES To define the allergic profile by components in wasp allergic patients. To study the usefulness of specific IgE to components in cases of double sensitisation. MATERIALS AND METHODS Wasp allergic patients who needed Polistes and/or Vespula venom immunotherapy were included. Before immunothe...

The knowledge on molecular allergy diagnosis is continuously evolving. It is now time for the clinician to integrate this knowledge and use it when needed to improve the accuracy of diagnosis and thus provide more precise therapeutic and avoidance measures. This review does not intend to comprehensively analyze all the available allergen molecules, but to provide some practical clues on use and...

BACKGROUND Fruits and vegetables may contain both labile and stable allergens. The former induce only OAS, whereas stable allergens may induce systemic reactions. Component-resolved diagnosis (CRD) of allergy to plant foods is therefore essential for the clinical management of allergic patients. METHODS 80 adults allergic to plant foods underwent SPT with purified natural date palm profilin (...

component-resolved  diagnosis (crd) using microarray technology has recently been introduced  with the  aim to  improve diagnosis of allergy. the  aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (spt). 45  patients  with  allergic rhinitis  were studied  (16 children  and  29  adults). spt  to dermatophagoides ...