Cortical bone, found in the central part of long bones like femur, is known to adapt to local mechanical stresses. This adaptation has been linked exclusively with Haversian remodelling involving bone resorption and formation of secondary osteons. Compared to primary/plexiform bone, the Haversian bone has lower stiffness, fatigue strength and fracture toughness, raising the question why nature ...

Impact Loading and Functional Tissue Engineering of Articular Cartilage by Roman M. Natoli This thesis presents two advances for alleviating the problem of articular cartilage degeneration: mitigating degradative changes that follow mechanically induced injuries and growing functional neo-cartilage for diseased tissue replacement. Experiments demonstrate that cartilage subjected to a single, no...

The ability to predict load-bearing capacity during the consolidation phase in distraction osteogenesis by non-invasive means would represent a significant advance in the management of patients undergoing such treatment. Measurements of stiffness have been suggested as a promising tool for this purpose. Although the multidimensional characteristics of bone loading in compression, bending and to...

The present article presents a method for assessing the radial stiffness of nitinol stents. An idealized stent model was created, and its radial stiffness was calculated by means of finite element modeling. The calculations were validated against experimental measurements. The variation of radial stiffness with geometrical dimensions was calculated, and the effect of increasing radial stiffness...

Collagen content and tensile properties of engineered articular cartilage have remained inferior to glycosaminoglycan (GAG) content and compressive properties. Based on a cartilage explant study showing greater tensile properties after chondroitinase ABC (C-ABC) treatment, C-ABC as a strategy for cartilage tissue engineering was investigated. A scaffold-less approach was employed, wherein chond...

Passive stiffness characteristics of isolated cardiac myocytes, papillary muscles, and aortic strips from male Holtzman rats fed a copper-deficient diet for approximately 5 wk were compared with those of rats fed a copper-adequate diet to determine whether alterations in these characteristics might accompany the well-documented cardiac hypertrophy and high incidence of ventricular rupture chara...

OBJECTIVE Acetabular labral tears predominantly affect young patients and are a source of hip pain in the athlete. Four causes of the initiation of labral tears have been proposed; trauma, hypolaxity of the anterior capsule, dysplasia and bony impingement. A further cause could be reduced biomechanical properties in the area most susceptible to tears. However, no work has defined these properti...

A coupon level comparative test method was developed to assess the foldability of thin flexible materials used in deployable structures. The subject materials support tensile and compressive loads; they are not cloth-like. The non-destructive method consists of a tensile stiffness test and a compressive buckling test and reveals changes in coupon properties that could result from locally extrem...

in this article, vibration analysis of an euler-bernoulli beam resting on a pasternak-type foundation is studied. the governing equation is solved by using a spectral finite element model (sfem). the solution involves calculating wave and time responses of the beam. the fast fourier transform function is used for temporal discretization of the governing partial differential equation into a set ...

INTRODUCTION The neutral zone, defined as the region of minimal passive stiffness [1], has been used to standardize the testing posture of functional spinal units (FSU) for in-vitro biomechanical studies. Typically, this region is determined experimentally through range of motion (ROM) tests, from which the applied moment and measured angular displacement are used to define the FSU’s passive st...