The acute respiratory distress syndrome (ARDS) is characterized by fluid accumulation in small pulmonary airways. The reopening of these fluid-filled airways involves the propagation of an air-liquid interface that exerts injurious hydrodynamic stresses on the epithelial cells (EpC) lining the airway walls. Previous experimental studies have demonstrated that these hydrodynamic stresses may cau...

BACKGROUND AND PURPOSE Preoperative embolization expands the spectrum of meningioma that can be operated on safely. Our goal was to achieve the distalmost loading of the vascular bed and confluent tumor necrosis with a fibrin glue preparation in the preoperative embolization of meningiomas. METHODS Between 1992 and 1997, 80 patients with a meningioma had diagnostic angiography with a standard...

Ishak (modified Knodell score) and METAVIR scores are the most widely accepted scoring systems for assessment of fibrosis and necroinflammation in dealing with chronic hepatitis C. In METAVIR, only interface hepatitis and lobular necrosis determine the grade of activity, while in Ishak, portal infiltrate and confluent necrosis are included with the two previous parameters. Confluent necrosis is...

A 51-year-old woman presented to the ED for severe, intractable pain due ulcerated skin lesions. She reported an initial presentation of patches and thin plaques, earlier biopsy was interpreted as consistent with early mycosis fungoides(MF). Within past year, widespread ulcerations developed. On exam, there were confluent ulcers necrosis, surrounded by erythematous distributed across chest, bac...