Background: Mayer - Rokitansky - Kuster - Hauser (MRKH) syndrome is characterized by congenital aplasia of the uterus and the upper part of the vagina in women showing normal development of secondary sexual characteristics and a normal 46, XX karyotype. Congenital anomaly of the female genital tract, estimated to occur in approximately 1 in every 5,000 females. It is caused by a failure of deve...

Duplication of the vas deferens is a very rare congenital anomaly in which two vasa deferentia coexist within the spermatic cord. Duplication of the vas deferens can be found during herniorrhaphy, vasectomy, and varicocelectomy performed on the spermatic cord or around the spermatic cord. However, it is estimated that the incidence of duplication of the vas deferens is under-reported and under-...

Carlin, Ryan W., Rebecca R. Quesnell, Ling Zheng, Kathy E. Mitchell, and Bruce D. Schultz. Functional and molecular evidence for Na -HCO3 cotransporter in porcine vas deferens epithelia. Am J Physiol Cell Physiol 283: C1033–C1044, 2002. First published May 22, 2002; 10.1152/ ajpcell.00493.2001.—This study focused on the role of sodium-bicarbonate cotransporter (NBC1) in cAMP-stimulated ion tran...

Congenital absence of the vas occurs in up to 1% of men. Congenital unilateral absence of the vas deferens can be related to cystic fibrosis transmembrane conductance regulator mutations or in 79% of cases, renal agenesis. We present a case of each, diagnosed in children at operation for elective inguinal hernia repairs. One patient had associated ipsilateral renal agenesis with a normal cystic...

This study focused on the role of sodium-bicarbonate cotransporter (NBC1) in cAMP-stimulated ion transport in porcine vas deferens epithelium. Ion substitution experiments in modified Ussing chambers revealed that cAMP-mediated stimulation was dependent on the presence of Na(+), HCO, and Cl(-) for a full response. HCO-dependent current was unaffected by acetazolamide, bumetanide, or amiloride b...

Accepted for publication June 22, 2012. Study received institutional review board approval. * Correspondence: Androfert, Andrology and Human Reproduction Clinic, Center for Male Reproduction, Av. Dr. Heitor Penteado, 1464, Campinas, São Paulo 13075-460, Brazil (telephone: 55 19 3295-8877; FAX: 55 19 3294-6992; e-mail: [email protected]). Purpose: We evaluated the retrieval rates and re...

PURPOSE We evaluated the retrieval rates and reproductive outcomes of percutaneous sperm retrieval according to the cause of obstructive azoospermia. MATERIALS AND METHODS We retrospectively studied the records of 146 men with obstructive azoospermia who underwent sperm retrieval for intracytoplasmic sperm injection. Patients were grouped by the cause of obstruction, including 32 with congeni...

BACKGROUND Duplication of vas deferens is a very rare congenital anomaly with only a few cases reported in the literature. Injury to vas deferens is a recognized complication during hernia surgery and the possibilities of injury may increase with lack of awareness of this anomaly. CASE REPORT A-31-year old gentleman with unilateral duplication of vas deferens that was diagnosed during right s...