background: it has been well documented that left ventricular hypertrophy (lvh) is an independent factor for cardiac death in children. the epidemiologic information reveals that there is a very high prevalence of lvh in children with chronic renal failure (crf). the purpose of this study was to evaluate the existence of left ventricular hypertrophy, its severity and other cardiac abnormalities...

iniencephaly is a rare kind of neural tube defect that is classified into two types of iniencephaly apertus and iniencephaly clausus. this anomaly could be diagnosed prenatally by obstetric ultrasonography and terminated by therapeutic abortion; however, it could be undiagnosed until birth similar to our case due to the abnormal position of the fetus or lack of experience of the sonographer. du...

nuchal translucency (nt) measurements in the first trimester screening between 11 and 14 weeks’ gestation are regarded as a clear marker for aneuploidies. the presence of a thickened nt, even if the karyotype is normal, can be associated with structural abnormalities. having an abnormal screening of nt, parents and physicians could face dilemma over abortion particularly in a case of ivf/icsi f...

Introduction: Along with advances occurring in cardiopulmonary bypass (CPB) including improved anesthesia intubation and early surgical interventions, it has become possible to correct life-threatening congenital heart anatomic abnormalities in patients. Our study aimed to collect information from one of the most important centers of pediatric cardiac surgery in Iran since there is limited info...

We report a series of five patients with congenital heart defects in whom a prenatal diagnosis of 22q11 deletion has been made. The accurate cardiac and cytogenetic diagnoses were made between 20 and 23 weeks' gestation in all cases and the cardiac findings were all confirmed postnatally. The cardiac abnormalities included tetralogy of Fallot with absent pulmonary valve, pulmonary atresia with ...

Objective: To define the incidence of brain and kidney anomalies in newborns with significant congenital heart disease admitted to the cardiac intensive care unit at Nicklaus Children’s Hospital. Study Design: A retrospective chart review of head and renal ultrasound was studied for newborns who were admitted with significant congenital heart disease to Nicklaus Children’s Hospital cardiac inte...

progressive osseous heteroplasia is a rare inherited disease that begins with skin ossification and proceeds into the deeper connective tissues. the disease should be distinguished from other genetic disorders of heterotopic ossification including fibrodysplasia ossificans progressiva (fop) and albright hereditary osteodystrophy (aho). we report a case of progressive osseous heteroplasia in a t...

now-a-days truncus arteriosus has been known as “common arterial trunk” (cat) and is an uncommon congenital cardiac defect presenting in about 1-3% congenital heart disease. environmental and genetic factors effects on incidence of cat and other conotruncal anomalies. the majority patients with cat and 22q11 deletion have other anomalies such as hypoplasia or aplasia of the thymus or parath...

* Four cardiovascular abnormalities account for the great majority of reported cases of sudden cardiac death in young athletes: hypertrophic cardiomyopathy (a pathologically enlarged heart), congenital (inherited) abnormalities of the coronary arteries, dissecting aortic aneurysms (bulging of the aorta with blood passing between layers of the arterial wall) in athletes with Marfan syndrome (a c...